Dr Jesil Mathew A

Associate Professor

Date of Joining: 25.05.2005

Department of Pharmaceutical Biotechnology

CURRENT ACADEMIC ROLE & RESPONSIBILITIES

    Jesil Mathew A is Associate Professor in the Department of Pharmaceutical Biotechnology, MCOPS. He is involved in 

    • Conducting theory and practical classes for BPharm, PharmD and MPharm students.
    • Recognised PhD Guide
    • Departmental ISO custodian. Certified Internal Auditor, ISO 9001:2000 QMS.

SUBJECTS CURRENTLY TEACHING

Subject Semester / Year
Biochemistry Second semester BPharm
Medicinal Biochemistry First year PharmD
Bioprocess Engineering and Technology First Semester MPharm
Pharmaceutical Biotechnology Practical 1 First Semester MPharm
Bioinformatics and Computational Biotechnology Second Semester MPharm
Biological Evaluation of Drug Therapy Second Semester MPharm

ACADEMIC QUALIFICATIONS

Degree Specialisation Institute Year of passing
PhD Pharmaceutical Biotechnology Manipal Academy of Higher Education 2010

Experience

Institution / Organisation Designation Role Tenure
Department of Pharmaceutical Biotechnology, MCOPS Associate Professor 2013-Present
Department of Pharmaceutical Biotechnology, MCOPS Assistant Professor – Selection Grade 2013 till 2013 November
Department of Pharmaceutical Biotechnology, MCOPS Assistant Professor 2010-2013
Department of Pharmaceutical Biotechnology, MCOPS Lecturer- Senior Grade 2008-2010
Department of Pharmaceutical Biotechnology, MCOPS Lecturer 2005-2008
Grace College of Pharmacy, PalakkadGrace College of Pharmacy, Palakkad Lecturer 2001-2005

AREAS OF INTEREST, EXPERTISE AND RESEARCH

Area of Interest

Molecular biology, immunology and Industrial Microbiology

Area of Expertise

Pharmaceutical biotechnology, microbiology, anti microbial testing, cell and molecular biology

Area of Research

Cancer biology, Studies on microbial biofilms and drug resistance Microbial products of therapeutic and industrial importance

Professional Affiliations & Contributions

  • Life Member of Indian Association of Cancer Research
  • Life Member of European Federation of Biotechnology
  • Life Member of Association of Hospital Pharmacists of India
  • Life member of Association of Pharmacy Teachers of India.

Cross-talk between AMP-activated protein kinase and the sonic hedgehog pathway in the high-fat diet triggered colorectal cancer.

2023 Beena, T. B Jesil, M. A. Harikumar, K. B

Archives of Biochemistry and Biophysics.2023. 735, 109500.

A novel high throughput 96-well-based fluorimetric method to measure amikacin in pharmaceutical formulations: development using response surface methodology.

2022 Maxwell, A Mary, E., Ghate, V. Aranjani, J. Lewis, S

Luminescence. 2022. 37, 6, p. 930-943 14 p.

Awakening sleeper cells: a narrative review on bacterial magic spot synthetases as potential drug targets to overcome persistence.

2022 Veetilvalappil, V. V Aranjani, J. M Mahammad, F. S Joseph, A

Current Genetics.2022. 68, 1, p. 49-60 12 p.

Nanoporous and nano thickness film-forming bioactive composition for biomedical applications.

2022 Chevala, N. T Kumar, L Veetilvalappil, V. Mathew, A. J Paonam, B Mohan, G Shastry, S Balasubramanian, K. Rao, C.M

Scientific Reports. 2022. 12, 1, 8198.

Pathogenic arsenal of Pseudomonas aeruginosa: an update on virulence factors

2022 Veetilvalappil, V. V Manuel, A Aranjani, J. M Tawale, R Koteshwara

Future Microbiology. 2022. 17, 6, p. 465-481 17 p.

Antibiotics for patients with chronic low back pain and vertebral bone edemaome types of chronic low back pain

2013-01-01 Manuel A Aranjani J M

2013, British Medical Journal. Antibiotics for patients with chronic low back pain and vertebral bone edemaome types of chronic low back pain

Is it wise to practice modern medicine without proper knowledge?

2013-01-01 Manuel A Aranjani J M

2013, British Medical Journal. Is it wise to practice modern medicine without proper knowledge?

Immunomodulatory Activity of Complementary and Alternative Medicines.

Harikumar K Hardman R Aranjani J M Raveendran V V

2014, Evidence-Based Complementary and Alternative Medicine: eCAM, http://dx.doi.org/10.1155/2014/765107.

Biofi lm Production and Antibiotic Susceptibility of Planktonic and Biofi lm Bacteria of Canine Dental Tartar Isolates

Josyula Venkata Rao Atulya Manuel Koshi John

2014, Acta Scientiae Veterinariae, 2014. 42: 1202.

Research in veterinary Science. Volume 96, Issue 1, February 2014, Pages 25–27

Manuel Atulya Aranjani J Rao J V Rao C M

Research in veterinary Science. Volume 96, Issue 1, February 2014, Pages 25–27

Synthesis of methoxy substituted chalcones and in vitro evaluation of their anticancer potential."

K R Ethiraj F Nawaz Khan

Chemical biology & drug design (2013) Volume 82, Issue 6, pages 732–742,

Potential cytotoxic and apoptosis inducing agents: synthesis and evaluation of methoxy-substituted chalcones against human lung and cervical cancers.

K R Ethiraj F Nawaz Khan Aranjani J

Medicinal Chemistry Research. 2013 2013-02-22:1-10.

Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of Xanthium strumarium in transplantable tumors in mice.

Aranjani J Manuel A Mallikarjuna Rao C Udupa N

American Journal of Chinese Medicine. 2013;41(1):145-62

Synthesis and characterisation of novel 2, 4-diphenyloxazole derivatives and evaluation of their in vitro antioxidant and anticancer activity." Journal of Pharmacy Research.

Jessy Elizabeth Gubba Divya S. Dinakaran Vachala Ramaiah Selladurai Jeyaprakash

Article in press, Published online; doi:10.1016/j.jopr.2012.12.001

In vitro and in vivo evaluation of the efficacy of nanoformulation of siRNA as an adjuvant to improve the anticancer potential of cisplatin.

Koganti S Jagani H V Palainimuthu V R M C Rao

Experimental and Molecular Pathology. Volume 94, Issue 1, February 2013, Pages 137–147

Synthesis and cytotoxicity study of pyrazoline derivatives of methoxy substituted naphthyl chalcones.

Ethiraj K R Nithya P Krishnakumar V Nawaz F Khan

Research in Chemical Intermediates 1-9, 2012.

Monastrol mimic Biginelli dihydropyrimidinone derivatives: synthesis, cytotoxicity screening against HepG2 and HeLa cell lines and molecular modeling study.

Soumyanarayanan U Bhat V G Kar S S

Organic and medicinal chemistry letters 2: 23, 2012.

Synthesis and Biological Evaluation of new acetylated pyrazoline analogues

Kunal Suman Ruchi Kumari Atulya M Ethiraj K R

Pharmacologyonline 2: (2011) 1411-1416

HIV Vaccines: Present Scenario And Future Prospects

Atulya M J. Venkata Rao Palanimuthu Vasanth Raj

Pharmacologyonline 2: (2011) 90-103

Acute and subacute toxicity of chloroform and hexane extracts of root of Xanthium strumarium

Chamallamudi Mallikarjuna Rao Atulya Manuel Josyula Venkata Rao Nayanabhirama Udupa

Comparative Clinical Pathology DOI: 10.1007/s00580-011-1269-5

Multidrug resistant Salmonella typhimurium in kuttanadan ducklings

Atulya M Koshy John

Pharmacologyonline (2010)

Antimicrobial Profile of Extremophiles from Aqua to Terrestrial Habitats

Angel Treasa Thomas J. Venkata Rao V.M.Subrahmayam B. Venkatesh Kamath

Pharmacologyonline 1- (2009). 111-126

Antioxidant and antidiabettic activity of Mimosa pudica Linn in streptozotocin induced diabetic rats.

Atulya M Alex Joseph

Biomed 3(2) July – Sept 2008 155-164

Free Radical Scavenging and anticancer activity of Clerodendron paniculatum

Jeril John M. Manjunath Shetty

Pharmacologyonline: 3: (2008) 730-748

A preliminary assessment of the acute and subchronic toxicity profile of Phase2 : An α-amylase inhibitor

Harikumar Kuzhuvelil B Sabu Mandumpal C Kuttan Ramadasan

International journal of toxicology 2005, vol. 24, No.2, 92-105

Microbiology in Practice; a laboratory manual for pharmacy students. Practical Manual for B.Pharm students.

Published inhouse for internal circulation.

Cancer chemopreventive and therapeutic properties of fruits and vegetables against head and neck malignancies.

Aranjani J M Padmavathi G Kunnumakkara A B

In Kunnumakkara, A.B. (ed), Anticancer Properties of Fruits and Vegetables. A Scientific Review. World Scientific publishers. (In press)

Nanotechnology and Environment (2013) Udupa N (ed), Exploring nanotechnology in healthcare

Aranjani J M Rao J V Manuel A Balasubramanyam M V

Manipal Academy of Higher Education press, Manipal, pages 182-192.

Letters to editor

Manuel A Aranjani J M

Outpatient antibiotic therapy: pros and cons. British Medical journal. 27th March 2013

Controlling swine flu: can we recommend vaccination?

Aranjani J M Manuel M

British Medical Journal. 29th March 2013

Arterial calcification in patient with end stage renal disease and diabetes

Aranjani J M Manuel M

British Medical Journal. 29th March 2013

Antibiotics for patients with chronic low back pain and vertebral bone edemaome types of chronic low back pain

Aranjani J M Manuel M

British Medical Journal. 15th May 2013

Is it wise to practice modern medicine without proper knowledge?

Aranjani J M Manuel M

British Medical Journal. 30th June 2013.

Assessment of genotoxic, cytotoxic and antioxidant properties of some medicinal plants that belong to family Asteraceae

2010-01-01 Kartheek Hebbar

2008-2010, MPharm Part-2.

Cloning expression and purification of a gene involved in type-2 diabetes

2010-01-01 Prashanth Sharma

2008-2010, MPharm Part-2.

Cloning and expression of rHIV envelope protein from E col

2011-01-01 G Satish Reddy

2009-2011, MPharm Part 2. Cloning and expression of a viral protein using bacterial host.

In-vitro anticancer ativities of selected synthetic chalcones

2011-01-01 Prashanth Nayak

2009-2011, MPharm Part – 2. In-vitro cytotoxic study of synthetic molecule.

Analytical characterisation of a therapeutic monoclonal antibody

2012-01-01 Chinthan Vayvala

2010-2012, MPharm Part-2. Analytical characterisation of transtuzumab.

Investigation of Biochemical and Physiological characteristics of Yeasts from Woodfordia fruiticosa- A study on the impact of stress factors playing key role in Ayurvedic Fermentations

2012-01-01 Karthik Nadentla

2010-2012, MPharm Part -2.

Screening of small molecule phosphodiesterase 4B (PDE4B) inhibitors

2012-01-01 Swetha Chinthala

2011-2012, MPharm Part -2.

Design and evaluation f nanoparticulate drug delivery systems for selected fluroquinalone antibiotics targeting biofilm based infections

2012-01-01 Nabeel Abdulrahman

2011-2012, MPharm Part -2. Development and characterisation of antibiofilm formulations.