About the Department

The Department of Reproductive Medicine & Surgery (RMS), previously known as Manipal Assisted Reproduction Center (MARC) has been offering a wide range of treatment programs for subfertile couples seeking assisted conception. It is backed by the experience of expert doctors and scientists who have taken specialized training abroad and have been working with subfertility problems since 1990. The pioneering technological improvements make the department one of the most advanced centers for the treatment of infertility in India.

 

The centre has a fully equipped andrology laboratory for male subfertility evaluation and semen banking for short-term and long-term storage. Embryology laboratory with all modern facilities including micromanipulation and laser hatching is another highlight of the center. Advanced techniques like oocyte pickup, ovarian cryopreservation, laparoscopic and hysteroscopic surgeries is done. 

 

 

Adjunct Faculty

Dr Siya Sharan Sharma, Adjunct Faculty

Consultant in Gynaecology & Obstetrics

Department of Obstetrics & Gynaecology

The Queen Elizabeth Hospital

Gayton Road, Kings Lynn, PE30 4ET, UK

 

Prof. Juan Antonio Garcia Velasco, Adjunct Professor

Full Professor of Obstetrics & Gynaecology

Director IVI Madrid

Av. del Talgo, 68, 28023

Madrid, Spain

Dr Howard Carp, Adjunct Professor

Senior Physician

Obstetrics & Gynecology

Sheba Medical Center

Tel Hashomer, Israel

Dr Sonal Panchal, Adjunct Professor

Consultant Sonography Specialist

Dr. Nagori’s Institute of Infertility and IVF

Ahmedabad, Gujarat, India

PhD Awarded/Ongoing

Phd Guide/Co-Guide:  , Professor & Head

 

Sl.No.

Guide / Co-Guide

Candidate Name

Year

1

Dr Pratap Kumar

Ms Ansha Patel

 

2019

2

Dr Pratap Kumar

Ms Azadeh Bagheri

 

2018

3

 

Dr Pratap Kumar

Mr Krishnananda Nayak

 

2018

4

Dr Pratap Kumar

Ms Preetha R

 

2016

 

5

Dr Pratap Kumar

Mr Dayanidhi Kumar

 

2015

 

6

 

Dr Pratap Kumar

Mrs Gayathri Nayak

 

2013

 

7

Dr Pratap Kumar

Ms Varshini J

2011

 

8

Dr Pratap Kumar

Mr Dinesh Upadhya

 

2010

 

9

Guide

Prof (Mrs) Bharati V Bellare

 

2003

 

 

https://manipal.edu/mu/academics/phd.html

 

 

Services Offred

 

·        Induction of Ovulation

·        Ultrasound & Doppler

·        Transvaginal Sonographic Procedures

·        Intra Uterine Insemination

·        In Vitro Fertilization with Embryo Transfer (IVF-ET)

·        Intra Cytoplasmic Sperm Injection (ICSI)

·        Laser assisted hatching

·        Vasal, Epididymal & Testicular Sperm Extraction (MESA/TESA)

·        Embryo and Semen Banking

·        Computer Aided Sperm Analysis (CASA)

·        Sperm DNA damage evaluation

·        Oncofertility

·        Laparoscopic & Hysteroscopic procedures

·        Comprehensive Male Infertility Evaluation and Treatment

·        Male Reproductive Laboratory

·        Donor Egg, Donor Sperm & Surrogacy

·        Blastocyst culture

·        Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)

·        Time lapse imaging of embryos

·        Fertility preservation (ovarian & testicular tissue cryopreservation)

 

Assisted Reproductive Techniques

 

Intrauterine insemination

Intrauterine insemination (IUI) is a simple, less invasive technique in which the husband or donor sperm is placed in the womb using a catheter. IUI is indicated for the treatment of low sperm count or unexplained infertility.

 

In vitro fertilization with Embryo Transfer

In Vitro Fertilisation with Embryo Transfer (IVF) is a procedure that involves retrieving the eggs from the wife after sufficient medication to stimulate the ovaries to develop many follicles. The eggs are fertilized in the dish using husband’s sperm.

 

Intracytoplasmic sperm injection (ICSI)

Intracytoplasmic Sperm Injection (ICSI) is used to treat couples who previously had failure in achieving conception due to the male partner’s extremely low number of normal sperm or with unexplained infertility.

 

Third party reproduction - Donor Eggs, Donor Sperm and Surrogacy

For women experiencing failure of their ovarian function and women over age of 40 with poor quality eggs, the use of donated eggs from another woman may be the best option to achieve conception. Our semen bank provides donor sperm for use in IUI and IVF when the husband has no sperm or if he has any genetic disorders.

 

Laser Assisted Hatching

It is a process to assist the embryos to break the zona pellucida (ZP) using laser in order to attach to the womb to increase the chance of pregnancy. 

 

Research

The department focusses on research programmes for improving the quality of management of sub-fertile couples. Research works on animal models are being carried out and this is one of the IVF centers in the country associated with a university medical college.

 

 

 

List of ongoing projects:

S.No.

Title of the grant

Granting agency

Co-Investigator

Duration of the project

1.

Targetted and Non-Targetted Approaches to Investigate Uterine Microenvironment in Women with Recurrent Implantation Failure

Indian Council of Medical Research, New Delhi, India & National Institute for Research in Reproductive Health (NIRRH),

Dr Pratap Kumar

Dr Anjali Suneel Mundkur

2021 -

2.

Role of Placental Monocarboxylate Transporter 8 (MCT8) expression on adverse pregnancy outcomes in Indian population

Indian Council of Medical Research, New Delhi, India

Dr Vidyashree G. Poojari

2021-2023

 

List of completed projects:

S.No.

Title of the grant

Granting agency

Principal Investigator

/ Co-Investigator

Duration of the project

1

An observational study to evaluate the follicular and endometrial response in couples with unexplained infertility undergoing micronized clomifene citrate stimulated intrauterine insemination

Walter Bushnell Laboratories Pvt Ltd., Uttarakhand, India

 

 

Dr Pratap Kumar

Principal Investigator

 

2017-2019

2

Clinical experience with micronized estradiol valetate tablets in endometrial preparation

 

Martin & Harries Pvt. Ltd., Haridwar

Dr Pratap Kumar

Principal Investigator

2015-2016

3

Fertility preservation using Moringa oleifera leaf extract in mice treated with Chemotherapeutic agents and its mechanism

Indian Council of Medical Research (ICMR),

New Delhi

 

 

Dr Pratap Kumar

Co-investigator

2012-2014

4

A study to evaluate the impact of different controlled ovarian stimulation protocols on physical and psychological burden in patients undergoing In-Vitro Fertilization/In-Vitro Cytoplasmic Sperm Injection

GVK Bioscience Pvt. Ltd., Gurgaon, India

 

Dr Pratap Kumar

Principal Investigator

2012-13

5

Evaluation of laser manipulated embryos for their hatching potential, metabolic changes and laser induced effects

Indian Council of Medical Research (ICMR), Govt. of India

Dr Pratap Kumar

Co-investigator

2011-2014

6

Intermediates of calcium signal process as oocytes activating agents and development of an optimum culture medium for mouse parthenotes

Department of Biotechnology

(DBT), Govt. of India

Dr Pratap Kumar

Co-investigator

2011-2013

7

The impact of chromosomal and sub-chromosomal sperm abnormalities on the embryonic development and Assisted Reproductive Technology (ART) outcome

Department of Science and Technology (DST), Govt. of India

Dr Pratap Kumar

Co-investigator

2010-2013

8

Evaluation of sperm chromatin modification, sperm methylation errors and reproductive toxicity in radiation health workers

Indian Council of Medical Research (ICMR), New Delhi

Dr Pratap Kumar

Principal Investigator

2009-2012

 

 

Publications

 

1. Shaiesta Amreen, Pratap Kumar, Priyanka Gupta, Pragna Rao. Evaluation of oxidative stress and severity of endometriosis. Journal of Human Reproductive Sciences. January – March 2019 ;12(1);40-46.

2. Shubhashree Uppangala, Gail Fernandes, Sujith Raj Salian, Pratap Kumar, Riccardo Talevi, Guruprasad Kalthur, Satish Kumar Adiga. Reduced ovarian response to controlled ovarian stimulation is associated with increased oxidative stress in the follicular environment. Reproductive Biology; 20(3);September 2020:402-407.

 

3. Ansha Patel, PSVN Sharma, Pratap Kumar. “Application of Mindfulness-Based Psychological interventions in Infertility”. Journal of Human Reproductive Sciences. January-March 2020;13(1);1-21.

4. Spoorthy Venkatesh, Anjali M, Akhila Vasudeva, Pratap Kumar. “Sliding sign and gel sonovaginography: A sneak peek prior to laparoscopy in patients with endometriosis”.  Journal of Human Reproductive Sciences. May 2020;13(1);26-30.

5. Ansha Patel, PSVN Sharma, Pratap Kumar. Psychiatric disorders in Women seeking fertility treatments: A clinical investigation in India. International Journal of Fertility and Sterility. April - June 2020;14(1);68-71.

 

 

 

Gallery

Contact Us

Adress:

Google map:  https://maps.app.goo.gl/T31CuYJNnUVsvnseA

Email: rms.kmc@manipal.edu

Phone number: +91 (0)820-2922162 / 2922027