About the Department

The department of Biochemistry was established in the year 1968, following the founding of Kasturba Medical College, Manipal, in 1953. The department educates medical students at the undergraduate level. It also provides MD and MSc in Medical Biochemistry postgraduate programs. The department also conducts regular CMEs for its postgraduate students and faculty. The diagnostic lab at the Biochemistry department is managed by a group of experienced and talented faculty involved in teaching and research. The diagnostic laboratory provides services to over 4,000 outpatients and inpatients per day.

This lab is NABL accredited caters to all patients visiting our hospital, and acts as a referral laboratory for private hospitals and physicians practicing in the surrounding areas. The lab has two specialty areas: a center of excellence for inborn error of metabolism screening and analytical toxicology, both of which were established in 2012 and 2015. Approximately two lakh thirty thousand tests are handled by the laboratory every month. The laboratory is committed to maintaining the highest quality of performance using the latest technology and equipment to provide rapid and reliable results for the patient in the shortest turnaround time.

Faculty and postgraduate students are encouraged to do research and publish scientific papers. In 2020-21, the faculty contributed 28 publications in International and National Scopus-indexed journals. Many Biochemistry faculty members have written articles in various newspapers published by the local media and presented in many television/radio programs aired by local channels.

The Biochemistry department and the other lab departments are interconnected to the hospital by a Laboratory Information System (LIS) for speedier and more accurate reports. Samples are bar-coded and fed into the equipment, automatically performing the tests indicated by the bar code. The test results obtained are instantly interphased online to the doctor's desk after verification eliminating transcriptional errors.

Adjunct faculty

We have adjunct faculty at the national & international level from different specialty areas, including research and industry. Regular online interactions are conducted with our adjunct faculty, helpful to our students to get insight into their field.

 

Dr. Barnali Das MD

Consultant Laboratory Medicine,

Kokilaben Dhirubhai Ambani Hospital & Medical Research Institute,Mumbai, Maharashtra

Dr. Anibh M Das, MD., PhD

Professor Paediatric Nephrology, Hepatology and Metabolic Disorders  Hannover Medical School, Hannover        

Dr. Shilpy Sharma

Ph.D. UGC-Assistant 

Professor Department of Biotechnology,

Savitribai Phule,Pune  

 

                                                  

Dr. Sandeep Sewlikar  

ROCHE Diagnostics, Pvt Ltd.

 Mumbai, India

Dr. Annayya Rao Aroor

MBBS, MD, PhD, MNAMS, FACBI,DABCC FAACC

University of Missouri, School of Medicine,

Columbia, MO

 

Series of guest lecture on Inborn Errors of Metabolism by Dr. Anibh Martin Das on 17th & 18th September 2019.

 

Talk on Enigma behind Thyroid Function Tests- Standardization Efforts by Dr.Barnali Das at  ACBICON 2018.

 

Alumni

Name

Degree

Year of Passing

Current Affiliation

Dr Wilma Delphine Silvia CR

MD- Biochemistry

1999

Prof & HOD, Dept of Biochemistry, Shri Atal Bihari Vajpayee Medical College and Research Institute & Principal, Shri Atal Bihari Vajpayee Institute of Allied Health Sciences, Bangalore-560001

Dr. Shivaraj Gowda

MD - Biochemistry

2000

Professor Dept of Biochemistry Subbaiah Institute of Medical Sciences, Shimoga, Karnataka

Dr Sharanabasappa M

MD - Biochemistry

2003

Professor of Biochemistry and Lab Director - Central Laboratory, Basaveshwar Hospital, Kalaburagi, Karnataka

Dr.Parineetha P B

MD - Biochemistry

2004

Senior Consultant and Head, Biochemistry section, Lab Services, Apollo Hospital,  BG Road , Bangalore 560076

Dr. Shashidhar KN

MD - Biochemistry

2004

Professor, Sri Devaraj Urs Academy of Higher Education and Research, Kolar, Karnataka

Dr.Anushre Prasad

MD - Biochemistry

2008

Specialist Clinical Chemistry, NMC Speciality Hospital , AI Nahda, UAE

Dr. Ayaz Khurram Mallick

MD - Biochemistry

2009

Associate Professor, Dept. Of Clinical Biochemistry, College of Medicine, King Khalid University, Abha, Saudi Arabia

 Dr. Vivek Joshi

MD - Biochemistry

2010

Associate Professor

Biochemistry & Genetics

Kentucky College of Medicine, Kentucky, USA

Dr. G Maheshwar Reddy

MD - Biochemistry

2011

Lab Director at YODA Lifeline Diagnostics Pvt Ltd, Hyderabad, Telangana

Dr Divya C

MD - Biochemistry

2011

Consultant Biochemist,

BBMP Hi-Tech laboratory,

H Siddaiah Referral Hospital, Bangalore, Karnataka

Dr Sweta Shivashanker

MD - Biochemistry

2012

Consultant Biochemistry, Columbia Asia Referral Hospital, Yeshwanthpur. A Unit of Manipal Hospitals, Bengaluru, Karnataka

Dr. Meenakshi Sundaram A.S

MD - Biochemistry

2013

Assistant Professor, PSG Institute of Medical Sciences and Research, Coimbatore, TN

Dr.Ketki Khandhadiya

MD - Biochemistry

2014

Associate Professor, Heritage Institute of Medical Sciences, Varanasi - UP.

Dr. Mrinal Gupta

MD - Biochemistry

2014

Assistant Professor
Dept. of Biochemistry
Govt. Medical College & Hospital,

Kathua(J&K) 184102

Dr Priyanka Datta

MD - Biochemistry

2015

Demonstrator, Nil ratan Sircar Medical College and Hospital, Kolkata, West Bengal

Dr. Kriti Singh

MD - Biochemistry

2015

Consultant Biochemistry and Quality Manager, Columbia Asia Hospital Sarjapur Road, Bangalore, Karnataka

Dr. Indranil Ghoshal

MD - Biochemistry

2016

Consultant Biochemist, Belle Vue Clinic, Kolkata 700017

Neelam M Pawar

MD - Biochemistry

2018

Assistant Professor, Kasturba Medical College- Mangalore, Mangalore, Karnataka.

Dr John G

MD - Biochemistry

2018

Lab Director, Grace Lab, and diagnostics, Chidambaram, Tamil Nadu

Dr Shravya Poduri 

MD-Biochemistry 

2018 

Perusing MD-Pediatrics 

Dr Vaideki B 

MD-Biochemistry 

2019 

Assistant Professor, 

Kasturba Medical College, Manipal,  

MAHE, Manipal 

Dr Arjun Asok 

MD-Biochemistry 

2022 

Senior Resident, 

Kasturba Medical College, Manipal,  

MAHE, Manipal 

MD – Postgraduate Students

MSc. Biochemistry/ PhD

PhD Scholars

PhD

The Department of Biochemistry offers regular Ph.D. for the eligible candidates. Since 1979 sixty candidates have been successfully awarded doctorate degree, and the department currently has five recognized Ph. D. guides and four registered students. MAHE also offers fellowships to excellent candidates. For more information on Ph.D. with us, please click here (please show this link https://manipal.edu/mu/academics/phd.html )

 

PhD Ongoing

Click Here

 

Awarded

 

Sl No

Name

Year

1

Dr. (Mrs.). S. Sumathi

1979

2

Dr.B Ramakrishna  Nayak

1980

3

Dr. P Gopalakrishna Bhat

1981

4

Dr. B Shivaraj

1981

5

Dr. A Ramesh Bhat

1982

6

Dr. K Krishna Sharma

1982

7

Dr. G Chandrashekar

1983

8

Dr. K Sudhakar Prabhu

1984

9

Dr. A . R. Aroor

1984

10

Dr. K Rambabu

1984

11

Dr. S. L Udupa

1985

12

Dr. Raju Thomas Jacob

1986

13

Dr. R. H Nagaraj

1987

14

Dr. A. V. Moideen Kutty

1988

15

Dr. N. Mallikarjuna Rao

1988

16

Dr. S. Swaminathan

1988

17

Dr. S. Sujatha

1988

18

Dr.(Mrs.) K. Beena Rai

1988

19

Dr. Anuradha Kumar

1989

20

Dr. (Ms.) Poornima Kamath

1990

21

Dr. (Mrs.) Pragna Rao

1991

22

Dr. Nagaraja Kumari

1991

23

Dr. (Mrs.) Gladys D’Souza

1991

24

Dr. (Mrs.) Maya Roche

1991

25

Dr. (Ms.) Vidya Prabhu

1993

26

Dr. (Mrs.) Malathi Kumudam

1993

27

Dr. (Mrs.) Manjula Shantaram

1993

28

Dr. H. Rajendra Kedlaya

1995

29

Dr. R. Senthil  Kumar

1995

30

Dr. H. Madhukar Mallya

1997

31

Dr. Shivananda Nayak B

1997

32

Dr. (Mrs.) Shaila H. P

1998

33

Dr. (Mrs.) Gayathri M Rao

1999

34

Dr. (Mrs.) Sudha K

1999

35

Dr. Raghothama C

1999

36

Dr. Sulochana Devi

1999

37

Dr. Usha Kumari

1999

38

Dr. (Mrs.) Nandini H. K

2000

39

Dr. Vijayalakshmi Varma P. R

2000

40

Dr. Padmanabha udupa E.G

2001

41

Dr. Jagadish Ulloor N

2002

42

Dr. Shivarajashankar Y.M

2002

43

Dr. Shivashankara A.R

2002

44

Dr. Geetha Samak

2003

45

Dr. B Shivananda Baliga

2003

46

Dr. Shobha U Kamath

2003

47

Dr. Winston Costa Pereira

2003

48

Dr. Niveditha L Rao

2003

49

Dr. Guruprasad Rao

2005

50

Dr. Surekha Bhat

2005

51

Dr. Chandrika D Nayak

2005

52

Dr. Somashekar Shetty

2005

53

Dr. Revathi P Shenoy

2006

54

Dr. Vinutha R Bhat

2014

55

Dr. Yousef Rezaei Chianeh

2016

56

Dr. Jenu Maria Thomas

2017

57

Dr. Bhaskar Gaokar

2017

58

Dr. Azadeh Bagheri

2018

59

Dr. Ranjini H. S

2019

60

Dr. Prajna P Shetty

2021

Services Offered

24 X 7 Diagnostic Lab  

 The biochemistry department has a 24 X 7 fully air-conditioned diagnostic lab with high-end auto analyzers, which generates 10,000 lab reports per day for all the outpatients and inpatients visiting our hospital. A total of 27 lab technicians are working in 3 shifts to provide these services.    In addition to routine chemistry tests, specialized tests include therapeutic drug monitoring, hormones, and a first-trimester screening panel. The Turn Around Time (TAT) for the tests is a maximum of 6 hours in working hours and non-working hours is 8 hours.  The department has facilities to do all tests required for emergency management and routine care of patients within its premises. None of the emergency tests are outsourced. 

Metabolic Screening Lab

Due to a lack of investigative capabilities and financial constraints, a considerable proportion of inborn errors of metabolism (IEM) problems in children go undiagnosed in India. Lack of awareness about these IEM disorders in this region of south India has motivated us to start the IEM laboratory. The only IEM lab in this district's IEM lab, serving a population of around 50,00,000 people. Patients from Kerala, Karnataka, and Andhra Pradesh. Since its inception, it has generated more than 4000 reports. Dried blood spot (DBS) samples collected from newborn babies are screened for seven congenital disorders, including Congenital Adrenal Hyperplasia (CAH), Congenital Hypothyroidism, Maple Syrup Urine Disease (MSUD), Phenylketonuria (PKU), Glucose-6-phosphate dehydrogenase deficiency (G6PD), Biotidinase deficiency, and Galactosemia, under the Newborn Screening program. The other investigations carried out in the IEM lab are amino acid and vitamins quantitative estimation using an HPLC analyzer. Quantitative estimations of amino acids and vitamins are done using an HPLC analyzer.

Analytical Toxicology Lab

Kasturba Medical College is an important tertiary referral hospital serving 130,000,000 people in Karnataka, Kerala, and Andhra Pradesh. In order to support diagnosis, early intervention, and comprehensive care, the Analytical toxicology wing was started. This wing was established in collaboration with the Department of Biochemistry, Forensic Medicine, and Pharmacy Practice. This center offers a different panel of tests, including- drug abuse panel, pesticide panel; alcohol panel; narcotic panel, and heavy metal panel. Since its inception, it has generated more than 5000 reports.

 

Gas-chromatograph/Mass Spectrometer

A state-of-the-art equipment used in the separation and identification of molecules, the gas-chromatograph-mass spectrometer (GC-MS) was procured under the DST-FIST grant along with an equal contribution from MAHE. The equipment is under the Centre for Excellence in Inborn Errors of Metabolism (CE-IEM), Kasturba Medical College, Manipal, a joint venture between the Departments of Pediatrics, Biochemistry, and Medical Genetics.

Currently, the equipment is used to research a wide range of metabolites and for various ongoing interdepartmental research between the Departments of Biochemistry, Pediatrics, Toxicology, Haemato-oncology, surgical oncology, and medical oncology. CE-IEM actively encourages collaborations with individuals/departments who are interested in optimally using the infrastructure that the laboratory provides.

Research

As biochemistry is a core basic science department offering diagnostic services and supporting postgraduate and Ph.D. programs, it regularly conducts academic activities like CMEs and conferences. It has good research output in the form of publications.

Grants Sanctioned

Sl No

Project Title

Sponsor

Duration & sanctioned amount

1

To establish a newborn screening lab and to initiate the mass screening program to reduce the mortality and morbidity of newborn children

Vision Group on Science and Technology, Bangalore

2015-2018

Rs. 60 lakhs

2

Stars in Global Health: To study the need and viability of a newborn screening program in India

Grand Challenges Canada

2017-2018

$ 1,00,000 CAD

3

Establishment of the thyroid reference range for the Indian population

Roche Diagnostics

2017-2020

Rs. 50 lakhs

4

Estimation of pesticide levels in farmers of Karnataka

Government of Karnataka

2017-2021

Rs. 33 lakhs

5

Role of placental monocarboxylate transporter 8(MCT 8) expression on adverse pregnancy outcomes in the Indian population

ICMR Grant

2021 – 2023

 

Rs. 25 lakhs

List of Publications

Sl No

Title

Authors

URL

1

Diagnostic performance of C-reactive protein level and its role as a potential biomarker of severe dengue in adults (Q1 Journal)

Raghavendra Rao, Snehal Nayak, Akhilesh K Pandey, Shobha U Kamath *

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85089184956&doi=10.4103%2f1995-7645.289440&partnerID=40&md5=907f17e21339c47bb2ff6f8db9e1debb

2

Lifestyle Modification with Physical Activity Promotion on Leptin Resistance and Quality of Life in Metabolic Syndrome - A Systematic Review with Meta-Analysis

(Q2 Journal)

Parameshwar Anche , Arun G. Maiya, Shobha Ullas Kamath, B Ananthakrishna Shastry Ravishankar

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85103462512&doi=10.2174%2f1573399816666200211102917&partnerID=40&md5=342633c6ec87917ac12e45463b358ce8

3

Effect of Green, Tulsi, and Areca Teas on the Color Stability of Two Composite Resin Materials – an in vitro Spectrophotometric Analysis (Q2 Journal)

Akshata Patil,  Vidya-Saraswathi Muliya, Kalyana-Chakravarthy Pentapati, Shobha Kamath

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85092471775&doi=10.2147%2fCCIDE.S276858&partnerID=40&md5=f4c6d67c2aea4c4623f452619f3b54a0

4

Effect of photobiomodulation therapy on inflammatory cytokines in healing dynamics of diabetic wounds: a systematic review of preclinical studies (Q2 Journal)

Gagana Karkada , G. Arun Maiya , Nicolette N. Houreld , Praveen Arany , Mohandas Rao KG , Shalini Adiga , Shobha Ullas Kamath & Somashekar Shetty

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85098600255&doi=10.1080%2f13813455.2020.1861025&partnerID=40&md5=262f43ede056147ecdc2c9f6721cf4d6

5

Plasma levels of angiogenic and angiostatic factors after panretinal photocoagulation for proliferative diabetic retinopathy

 (Q2 Journal)

Bhaskar Gaonkar, Krishnananda Prabhu, Pragna Rao, Asha Kamat, Krishna Rao, Muralidhar Varma

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85091646799&doi=10.3269%2f1970-5492.2020.15.34&partnerID=40&md5=47fb7e5aacb4af1defbfe5fc53adb65f

Patents and Copywrite received:

1

Received copyright certificate for "Noninvasive tests for Diabetes Mellitus" Registration Number: CF- 4826/2021- short educational video - Copyright Office Govt Of India – 11/02/2020 – 216/2020- CO/CF

2

Received copyright certificate for “Post Analytical Sample Archival System” Diary No: 11940/2015- CO/L – registered on 03/04/2018 [Ref – BNP/CR/18 dated 9th August 2018; R.K Dewan & Co]

3

“System and method for locating and enabling retrieval of containers from a tray” has been filed at the Indian Patent Office on 05th July 2019 as a complete application. Application no. Accorded to the same is 201941027085.

4

“System, medical device and method for diagnosing medical conditions of a patient” has been filed at the Indian Patent Office on 24th August 2019 as a complete application. Application no. Accorded to the same is 201941034195.

5

“A biochemical detection strip and a method to detect an analyte” has been filed at the Indian Patent Office on 15th January 2020 as a complete application. Application no. Accorded to the same is 202041001862.

6

Received copyright for “Communication skill – Biochemistry Perceptive” Registration Number: CF-4655/2020 – Short educational video - Copyright Office Govt of India – 14/09/2020 - 2608/2020-CO/CF

7

Received copyright for Noninvasive tests for Diabetes mellitus: Registration Number: CF-4826/2021 – Short educational video - Copyright Office Govt of India – 11/03/2021 - 2616/2020-CO/CF

Achievements

WHO has listed Manipal Poison Detection Center in the directory of World Poison Centers on June 13, 2019

 

Gallery

Faculty

Contact Us

Address

Google Map: https://goo.gl/maps/YqwyYjXyjF2rwSsSA
Email: biochem@manipal.edu

Phone Number: +91-820-2922326