Dr Raghu Radhakrishnan

Professor, Oral Pathology, MCODS, Manipal; Director of International Affairs & Collaborations, Manipal Academy of Higher Education, Manipal.

MDS, PhD

Department of Oral Pathology

CURRENT ACADEMIC ROLE & RESPONSIBILITIES

    Dr Raghu Radhakrishnan is a Oral Pathologist at Manipal College of Dental Sciences, Manipal and the Director of Internatonal Affairs and Collaborations at Manipal Academy of Higher Education, Manipal. As a professor in the department of oral pathology, he is actively involved in teaching and supervising postgraduates. In his role as Director, International Collaborations, he is involved in fostering academic and research cooperation globally.

SUBJECTS CURRENTLY TEACHING

Subject Subject code Semester
Dental Anatomy, Embryology & Oral histology First year BDS
Oral Pathology and Microbiology Second and third year BDS
Oral and Maxillofacial Pathology MDS

ACADEMIC QUALIFICATIONS

Degree Specialisation Institute Year of passing
BDS TN Dr MGR Medical University 1994
MDS Oral Pathology and Microbiology Manipal College of Dental Sciences, Manipal 1997
PhD Oral Cancer Epigenetics Manipal 2009
Marie Curie Fellow Chemoprevention in oral cancer School of Clinical Dentistry, Sheffield, UK 2015
Wellcome Trust Fellow Oral Cancer Epigenetics Manipal Academy of Higher Education 2019-2024

Experience

Institution / Organisation Designation Role Tenure
Manipal Academy of Higher Education, Manipal Director, International Collaborations 2017 till date
Manipal Academy of Higher Education, Manipal Deputy Director, Research 2015-2017
The University of Sheffield, UK Marie Curie Fellow 2013-2015
Manipal College of Dental Sciences, Manipal Professor and Head 2010-2013
Manipal College of Dental Sciences, Manipal Professor 2008-2010
Manipal College of Dental Sciences, Manipal Associate Professor 2003-2008
Manipal College of Dental Sciences, Manipal Assistant Professor 1998-2003

Projects

Ongoing Projects:

1.  Title: Epithelial Reprograming of HOX Genes by Epigenetic Mechanisms and its implication to Oral Cancers.

IA/CPHI/18/1/503927                                                            

PI: Raghu Radhakrishnan                                                     

Duration: 01/09/19 - 01/08/24

EMR/2017/002792                                                                       

2. Title: Characterization of novel TGF-β1/SMAD regulated microRNAs in the rat model of oral Submucous Fibrosis

PI: Raghu Radhakrishnan

Duration: 25/09/18 - 24/9/21                                                                                                                                                  

3. TBI-GoK-Manipal-BioPharma                                     

PI: Raghu Radhakrishnan

Duration: 2/09/2018 – 1/09/2023                                                                                                                                                        

Title: Government of Karnataka – Manipal – Technology Business Incubator

Completed Projects

1. FP7-PEOPLE-2012-IIF                                     

CoPI: Raghu Radhakrishna

13/10/2013– 14/10/2015

Title: Understanding the functional role of Retinoic Acid Receptor Beta2 in the development of oral cancer

PhD Guide

Supervisor to two PhD Fellows

PhD Topic:

1.       Role of Epithelial Mesenchymal Transition in the Pathogenesis of Oral Submucous Fibrosis and its Implications in Malignancy

2.       Characterization of novel TGF-β1/SMAD regulated microRNAs in the rat model of oral Submucous Fibrosis

Collaborations

1. Mohit Sharma, National
Department of Oral Pathology, Sudha Rustagi College of Dental Sciences and Research, Greater Faridabad 121002, Haryana, India.

Pathogenesis of Oral Submucous Fibrosis

2. Fonseca FP, International

Department of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Molecular Pathogensis of Oral Squamous Cell Carcinoma

3. Keith Hunter, International

Integrated Biosciences, School of Clinical Dentistry, University of Sheffield, Sheffield, UK

Hox Genes and Oral Cancer

Grants 

Characterization of novel TGF-β1/SMAD regulated microRNAs in the rat model of oral submucous fibrosis and the effect of Resveratrol as an Anti-Fibrotic Agent.  SERB, DST, New Delhi (2018, 3 years); 3.448.500 (INR)

Epithelial Reprograming of HOX Genes by Epigenetic Mechanisms and its implication to Oral CancersThe Welcome Trust/DBT India Alliance (2019, 5  years); 35.551.271 (INR)

Contributions

· Sivapathasundaram B, Raghu AR. Anatomy of human salivary gland, Manual of Salivary Gland Diseases, 1st edition, Jaypee Brothers, 2-21, Year – 2013,

· Sivapathasundaram B, Raghu AR, Rajendran R. Physiology and Functional disorders of salivary glands, Manual of Salivary Gland Diseases, Jaypee Brothers, 55-66, Year – 2013,

· Raghu Radhakrishnan, Bijayata Shrestha, Dipshikha Bajracharya. Oral Cancer. Edited by Kalu U. E. Ogbureke, Published by InTech, Croatia, Year 2012

· Sivapathasundaram B, Raghu AR, Dental Caries, Shafer’s textbook of Oral Pathology, 8th Edition

· Sivapathasundaram B. Raghu AR, Dental Caries. Shafer’s textbook of Oral Pathology, 7th edition Volume: - Year: 2012, Elsevier, 419 – 474

· Sivapathasundaram B. Raghu AR, Dental Caries. Shafer’s textbook of Oral Pathology, 6th edition Volume: - Year: 2009, Elsevier, 409 – 473

· Sivapathasundaram B, Raghu AR, Dental Caries. Shafer’s textbook of Oral Pathology, 5th edition Volume: - Year: 2006, Elsevier, 567 – 658

· Radhakrishnan AN, Raghu AR. Periodontics Made Easy   Year: 2006, CBS Publishers

Awards and Recognition

Dates   

Award  

  Awarding Institution

2019

Member - Executive Council

Indian Association of Oral and Maxillofacial Pathologists

2019

Wellcome Trust Fellowship

Department of Biotechnology India Alliance

2017

Dr. TMA Pai Gold Medal

Best Research at Manipal College of Dental Sciences, Manipal

2015

Marie Sklodowska Curie Individual Fellowship

European Union’s Seventh Research Framework Programme (FP7) at the University of Sheffield

2013

Mentor – Best Case Report

XIII National Post Graduate Convention of IAOMP, Thirupathi, AP

2013

Mentor - Best Case Report, Best Review, Best paper on novel marker, Best poster configuration

National Midterm Conference of the IAOMP, Chennai, TN

2012

Best Teacher Award

Manipal College of Dental Sciences, Manipal University, Manipal

2012

Travel Fellowship

Council for Scientific and Industrial Research to attend the AAOMP meet at Minneapolis, MN, USA

2011

Mentor - Best Poster

Prevalence of Candida species in HIV positive subjects in Udupi District XX National Conference of IAOMP, Hyderabad

2011

Research Incentive Award

Manipal College of Dental Sciences, Manipal University, Manipal

2010

Travel Fellowship

Department of Science and Technology, Govt. of India to attend 15th International Congress on Oral Pathology and Medicine

2010

Travel Award

International Association of Oral Pathologists, to attend 15th International Congress on Oral Pathology and Medicine

2009

ISDR Fellowship

Indian Society of Dental Research

2007

Travel Fellowship

Department of Science & Technology to attend Gordon Research Conference on Cancer Genetics and Epigenetics at Barga, Italy

2006

Best poster

Manipal University Scientific meet, for the poster  “DNA methylation as an epigenetic marker in oral cancer

2003 – 2006

Faculty Research fellowship

Manipal Foundation for the PhD work titled “Molecular pathogenesis of human oral cancer by epigenetic mechanism

AREAS OF INTEREST, EXPERTISE AND RESEARCH

Area of Interest

1. Oral Cancer and Epigenetics 2. Molecular understanding of Oral submucous Fibrosis 3. Prognostic markers in early stages of oral cancer 4. Molecular mechanisms of oral carcinogenesis

Area of Expertise

1. Oral Cancer and Epigenetics 2. Molecular understanding of Oral submucous Fibrosis 3. Prognostic markers in early stages of oral cancer 4. Molecular mechanisms of oral carcinogenesis

Professional Affiliations & Contributions

1.       International Association of Oral and Maxillofacial Pathologists

2.       International Association of Oral and Maxillofacial Pathologists

Link for publication details:

https://www.scopus.com/authid/detail.uri?authorId=7103113006

Methylation regulated genes as diagnostic and prognostic marker for early detection of oral cancer--submitted to Regional Indian Patent Office, Chennai.