Manipal Institute of Regenerative Medicine (MIRM) was conceptualized to cater to the expanding need for qualified stem cell professionals in the health care sector in 2007. MIRM takes pride being Asia’s first consolidated scholastic and research program in Stem Cell Technology and Regenerative Biology. The broad aim of the Institute was to hone young students towards a carrier in Regenerative Medicine and Stem Cell Technology and generate qualified manpower trained in stem cell technologies to bridge the need for stem cell based therapeutics in India. MIRM offers courses at the Master’s and Ph.D. levels and has developed a strong course curriculum which encompasses concepts in developmental biology, principles of tissue engineering and clinical and non-clinical applications of stem cells. Apart from the academic curriculum, MIRM has a strong research component with principal investigators specialized in several cutting edge areas including neuro-regeneration, transplantation immunology, cancer stem cells, material research and cellular reprogramming. Exposure to stem cell research is facilitated by inclusion of electives and a one year rigorous project work in any specialization of stem cell biology under the able guidance of the principal investigators during the final year of Master’s program. Principal investigators support their research through regular extramural funding from government agencies like DST, DBT, ICMR, BIRAC and CSIR, in addition to international funding. Several quality publications have emerged from research conducted at MIRM and has contributed immensely to the know-how in regenerative medicine. MIRM students are appointed at several research positions in both industry, academia and health care sector indicating the success of mission initially conceptualized. MIRM is now a recognized hub for potential recruiters to get trained manpower in stem cell and cell biology technologies. Adjunct faculty from various national and international universities also contribute to teaching specialized topics and have formed a strong collaborative research network. We also foster entrepreneurship and commercial application through active industry collaborations.