Dr. S Jyothi Prasanna
Professor & Dean
Manipal Institute of Regenerative Medicine
Qualification: PhD
CURRENT ACADEMIC ROLE & RESPONSIBILITIES
Professor in the Manipal Institute of Regenerative Medicine.
SUBJECTS CURRENTLY TEACHING
| Subject | Semester / Year |
|---|---|
| Mechanisms of stem cell renewal | First Semester |
| Translation | First Semester |
| Transplantation | First Semester |
| Stem cell niches | Second Semester |
| Liver morphogenesis | Second Semester |
| Endoderm differentiation | Second Semester |
| Stem cells in tumorogenisis | Third Semester |
| Allogeneic stem cell transplantation | Third Semester |
| Homing of stem cells | Third Semester |
ACADEMIC QUALIFICATIONS
| Degree | Specialisation | Institute | Year of passing |
|---|---|---|---|
| PhD | Biochemistry | IISC, Bengaluru | 2005 |
| MPhil | Biotechnology | JNU, Delhi | 1998 |
Experience
| Institution / Organisation | Designation | Role | Tenure |
|---|---|---|---|
| Manipal Institute of Regenerative Medicine, Bangalore | Associate Professor | 2011-Present | |
| School of Regenerative Medicine, Bangalore | Group head, Adult Stem cell Group | Teaching and training MSC, Diploma, MPhil and PhD students | 2007-Present |
| School of Regenerative Medicine, Bengaluru | Assistant Professor | 2007-2011 | |
| Stem Cell Research Centre, Manipal Hospital | Research Scientist | Setting up the allogeneic clinical trials with human MSCs. Training and teaching JRFs and SRFs immunoassays relevant for setting up in vitro platforms to validate immuno-modulatory potential of allogeneic MSCs | 2006-2007 |
Comparative analysis of adult stem cells from different tissues reflects differences in cell surface profiles, plasticity and immuno-modulatory potential
2007-01-01 Divya Gopalakrishnan Satish Totey
Presentation at International Society for Stem Cell Research (ISSCR), Cairns, Australia .
Immuno-modulation by human bone marrow derived mesenchymal stem cells upon priming with pro-inflammatory cytokines
2009-01-01 Divya Gopalakrishnan BV Anoop Shilpa Rani
Presentation at International Society for Stem Cell Research (ISSCR), Barcelona.
Hierarchical organisation of cancer stem like cells (cscs) in human hepatocellular carcinomas (hcc): insights into the molecular machinery prevalent in csc like sub-populations
2010-01-01 Parvathy Venugopal Shilpa Rani Shankar BV Anoop
Presentation at International Society for Stem Cell Research (ISSCR) 8th Annual meeting , San Francisco, USA .
Mesenchymal stem cells from Bone marrow and Umbilical cord stroma as cellular and immune therapeutics: does the source matter?
2009-01-01
National Conference on Medical Biotechnology and Clinical Research held at IISc, Bangalore.
Mesenchymal Stem cells as cellular immune-modulators
2010-01-01
CME at Department of Biochemistry, KIMS (Kampegowda Institute of Medical Sciences), Bangalore.
AREAS OF INTEREST, EXPERTISE AND RESEARCH
Area of Interest
Hepatobiology, Trans-differentiation, Transplantation Immunology, Basic mechanisms of stem cell renewal and differentiation, Hormonal influences on stem cells and aging
Area of Expertise
Immunology, Hepatobiology, Stem cell biology
Area of Research
Elucidating the role of stem cells in injury resolution and repair, Factors influencing differentiation of embryonic and adult stem cells to endoderm derivatives, Hormonal elements in connective tissue differentiation-implications in obesity and osteoporosis
Professional Affiliations & Contributions
- Member of the Society of Biological chemists.
- Member of the International Society for Stem Cell Research (ISSCR).
- Editorial Board Member of International Journal of Stem Cell Research and Transplantation (IJST).
- Advisor of Stempeutics Research Pvt Limited.
Wharton’s Jelly Mesenchymal stem cells as off-the-shelf cellular therapeutics: A closer look into their regenerative and immune-modulatory propertiesm
2011-01-01 V Soumya Jahnavi
The Open Tissue Engineering and Regenerative Medicine Journal .
Pro-inflammatory cytokines, IFNgamma and TNFalpha, influence immune properties of human bone marrow and Wharton jelly mesenchymal stem cells differentially
Gopalakrishnan D Shankar SR Vasandan AB
2010, PLoS On, 5(2):e9016 .
Gene modulation and immune-regulatory roles of IFNgamma Cytokine
2009-01-01 Banishree Saha Bhagawat Chndrashekar Nandi D
Involvement of oxidative and nitrosative stress in modulation of gene expression and functional responses by IFN gamma in a hepatoma cell line
2007-01-01 Saha B Nandi D
2007, Int. Immunol., Vol 19(7), Pg 867-79.
The MHC-encoded class I molecule, H-2Kk, demonstrates distinct requirements of assembly factors for cell surface expression: roles of TAP, Tapasin and beta2-microglobulin
2004-01-01 Nandi D
Molecular Immunology, Elsevier, Vol 41, Pg 1029-45 .
Differential requirements for optimal cell surface expression of MHC class I molecules
2003-01-01 Nandi D
H-2Kk and H2-Dd 10th Proceedings of Asian Oceanian Biochemists and Molecular Biologists, Pg 152-160 .
5 Functional differences in mesenchymal stromal cells from human dental pulp and periodontal ligament
2013-01-01 Anoop Babu Vasandan Shilpa Rani Shankar Priya Prasad V Sowmya Jahnavi
Journal of Cellular and Molecular Medicine .
Master Adult Stem Cells from Corneal Tissue
2006-01-01
Patent No 1588 / CHE / 2006
Characterisation of Cancer stem cells from Hepatoblastomas
2010-01-01 Divya N
PG Student from Mahatama Gandhi University, Changancherry, Kerala.
Isolation and characterisation of human periodontal ligament derived stem cells
2009-01-01 Dr Deepa Ponniyan
MD student of Manipal College of Dental Sciences, Manipal University.
Comparison of stem cells isolated from human dental pulp and human exfoliated deciduous teeth
2007-01-01 Dr Vinay Rao
MD student of Dayanandsagar Instistute of Dental Sciences, Bangalore.
Tumour cell lines as model systems to evaluate the role of stem cell like cells in carcinogenesis
2009-01-01 Parvathy Venugopal
MSc student SORM, Manipal University.
Influence of 17-β Estradiol on cell survival and Differentiation potential of BMMSCs
2011-01-01 Joshua Keppen
MPhil student, SORM, Manipal University.
Characterisation and Mesenchymal stem cell properties of stromal cells isolated from Dental pulp and periodontal ligament
2012-01-01 Dr Manjunath N M
MPhil, SORM, Manipal University.
Effect of negative regulators of signalling on differentiation of Mesenchymal stem cells
2009-01-01 Sheetal Mary Sunny
MSc student Vellore Institute of Technology, Vellore University.