Dr Madhavan Nampoothiri G

Assistant Professor- Selection Grade

Department of Pharmacology


    Dr Madhavan Nampoothiri G teaches Human Anatomy and Physiology for I PharmD and I BPharm students and Pharmacology for MPharm students.


Subject Semester / Year
Anatomy and Physiology First Year B Pharm
Human Anatomy and Physiology First year PharmD
Pharmacology-II (Practicals) Third year PharmD
Principles of drug discovery MPharm Semester 1
Pharmacology-II (Practicals) MPharm Semester 1 and 2
Research work III and IV semester MPharm


Degree Specialisation Institute Year of passing
PhD Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education 2015
M Pharm Pharmacology Government Medical College, Thiruvananthapuram, Kerala 2009
B Pharm Government Medical College, Calicut, Kerala 2006


Institution / Organisation Designation Role Tenure
Department of Pharmacology, MCOPS Manipal Assistant Professor (Senior Scale) Teaching and Research July 2014-till date
Department of Pharmacology, MCOPS Manipal Assistant Professor Teaching and Research Jan 2011 till July 2014
Department of Pharmacology, MCOPS Manipal Lecturer Teaching July 2010 - January 2013
Educare Institute of Dental Sciences, Chattiparamba, Malappuram district, Kerala, India Lecturer Taught Pharmacology for II year BDS. 1 year 13 days

Drug eluting nanowafers as a treatment modality for ocular inflammation

Dr Madhavan as Co-Investigator

Funded by DBT


Area of Interest

Pharmacology of Neurodegenerative disorders, Insulin signalling in brain, Neuroinflammation, Substance P signalling in brain, Renal ischemia

Area of Expertise

Animal models of dementia, Evaluation of learning and memory

Area of Research

Insulin receptor signalling in neurodegenerative disorders

Professional Affiliations & Contributions

  • Received a Travel Grant, World Federation of Neurology, Osaka, Japan 2017. "Tachykinin receptor antagonist, N-acetyl L-Tryptophan alleviates spatial memory deficits in Alzheimer’s disease model in rats". XXIII World Congress of Neurology scheduled at Kyoto, Japan, September 16-21, 2017 .
  • Dr Madhavan and team have a collaboration with Griffith University, Australia
  • Member of Kerala State Pharmacy Council.
  • Received the “NAGAI-SHUKRI award” instituted by Asian Federation for Pharmaceutical Sciences for the pre-doctoral best paper presented at the 2nd Asian federation for Pharmaceutical Sciences conference 2011 held in Kualalumpur, Malaysia from 9-12 December, 2011.

  • Received Award for “Investigator from developing country” during XX world congress on Parkinson’s disease and related disorders held in Geneva, Switzerland from 8-11 December, 2013. 




Total number of publications: 27

Some of the important research papers are listed below. For more details, Please browse the following link- https://manipal.pure.elsevier.com/en/persons/madhavan-nampoothiri-g


Protective effect of rivastigmine against aluminium induced spatial memory impairment in rats

2013-01-01 C Mallikarjuna Rao Jessy john

International Journal of Multidisciplinary Research, 2013.

Prevalence of post stroke complications in South India: A Descriptive study

2013-01-01 Sreeraj K Thomas Iype Balan CS

International Journal of Pharmacy and Technology, 2012.

Colon targeted drug delivery system: A Review

2011-01-01 Koteshwara KB Naha Anup

International Journal of Research in Ayurveda & Pharmacy, 2011.

Nanosuspensions: A novel drug delivery approach

2011-01-01 Koteshwara KB Naha Anup Reddy MS

International Journal of Research in Ayurveda & Pharmacy, 2011.

Insulin blocks glutamate-induced neurotoxicity in differentiated SH-SY5Y neuronal cells

Madhavan Nampoothiri Neetinkumar Reddy Jessy John Nitesh Kumar Gopalan Kutty Nampurath C Mallikarjuna Rao

Behavioural Neurology, (2014) 1-8

Modulatory role of simvastatin against aluminium chloride induced behavioral changes in rats

Madhavan Nampoothiri Jessy John Nitesh Kumar Jayesh Mudgal Gopalan Kutty Nampurath C Mallikarjuna Rao

Behavioural Neurology, (2015) 1-9

Sesamol a lipid lowering agent ameliorates aluminium chloride induced behavioural and biochemical alterations in rats

Jessy John Madhavan Nampoothiri Nitesh Kumar Gopalan Kutty Nampurath C Mallikarjuna Rao

Pharmacognosy Magazine, 11 (2015) 327-336.

Atypical antidepressant activity of 3, 4-Bis (3,4-Dimethoxyphenyl) Furan-2,5-dione isolated from heart wood of Cedrus deodara, in rodents

Nitesh Kumar Daniel Dhayabaran Madhavan Nampoothiri Krishnadas Nandakumar Puratchikody A Natasha Lalani Karima Dawood Aanesha Ghosh

Korean Journal of Physiology and Pharmacology,18(5) (2014) 365-370.

Caffeic acid attenuates lipopolysaccharide-induced sickness behaviour and neuroinflammation in mice

Basu Mallik S Mudgal J Nampoothiri M Hall S Dukie SA Grant G Rao CM Arora D

Neurosci Lett. 2016 Oct 6;632:218-23. doi: 10.1016/j.neulet.2016.08.044.

Naringin and Rutin Alleviates Episodic Memory Deficits in Two Differentially Challenged Object Recognition Tasks

Ramalingayya GV Nampoothiri M Nayak PG Kishore A Shenoy RR Mallikarjuna Rao C Nandakumar K

Pharmacogn Mag. 2016 Jan;12(Suppl 1):S63-70. doi: 10.4103/0973-1296.176104

Behavioural Assessment of Nicotinic Acid, A GPR109a Receptor Agonist against Memory Deficit in Rats

Khurana, S Nampoothiri, M Mudgal, J

International Journal of Pharmaceutical Sciences Review and Research 2016, 40(1), pp.313-317

In Vitro Cytotoxicity Activity of Chrysin, Morin and Resveratrol Against MCF-7 Breast Cancer Cell Lines

Thomas, A Ranadive, N Nayak, H Surendran, S Nampoothiri, M Mudgal, J

 Biosciences Biotechnology Research Asia 2016, 13(3), pp.1633-1637

An Insight in to the Efficacy of Dehydrozingerone against Aluminium Induced Cognitive Dysfunction in Rats

 Rao, M.C Mudgal, J Nampoothiri, M

International Journal of Pharmaceutical Sciences Review and Research 2016, 39(1), pp.70-73

Effect of insulin on spatial memory in aluminum chloride induced dementia in rats

Nampoothiri M Kumar N Ramalingayya GV Nandakumar K Kutty NG Rao CM

Neuroreport. 28; 540-544, 2017 ( JCR Impact factor-1.39)

Interplay between adenosine receptor antagonist and cyclooxygenase inhibitor in haloperidol-induced extrapyramidal effects in mice

Arora D Mudgal J Nampoothiri M Mallik S.B Kinra M Hall S Anoopkumar-Dukie S Grant GD Rao CM

Metabolic brain disease 2018; 33 (4): 1045-1051. [IF-2.44]

N-acetyl-L-tryptophan, a substance-P receptor antagonist attenuates aluminum-induced spatial memory deficit in rats.

Fernandes J Mudgal J Rao CM Arora D Basu Mallik S Pai KSR Nampoothiri M

Toxicology mechanisms and methods. 2018; 28 (5): 328-334. [IF-1.94]

Catechin ameliorates doxorubicin-induced neuronal cytotoxicity in in-vitro and episodic memory deficit in in-vivo in Wistar rats

Cheruku SP Ramalingayya GV Chamallamudi MR Biswas S Nandakumar, K Nampoothiri, M Gourishetti, K. Kumar, N

Cytotechnology. 2018; 70 (1): 245-259. [IF-1.82]

Insulin combined with glucose improves spatial learning and memory in aluminium chloride-induced dementia in rats.

Nampoothiri M Ramalingayya GV Nandakumar K Kutty NG Rao CM

Journal of Environmental Pathology Toxicology and Oncology. 2017; 36 (2): 159-169. [IF-1.52]

An insight into the role of cyclooxygenase and lipooxygenase pathway in renal ischemia

Kinra M Mudgal J Arora D Nampoothiri M

European review for medical and pharmacological sciences, 2017, 21(21), pp.5017-5020. (IF-1.78)

Evaluation of tachykinin receptor antagonist, N-Acetyl-L-Tryptophan in Alzheimer's disease model in rats

Joylee Fernandes (2015-16)

MPharm dissertation

A study to evaluate the efficacy of caffeic acid in animal model of acute renal failure

Manas Kinra (2016-17)

MPharm dissertation

Evaluation of activity of CB2 cannabinoid receptor agonist and tachykinin receptor antagonist in animal models of neuroinflammation and depression

Puspita Sahu (2016-17)  

A study to evaluate the effect of neprilysin in renal ischemia reperfusion in rats.

Runali Sankhe (2018)

Deciphering the role of beta-caryophyllene against intracerebroventricular colchicine induced cognitive deficit in rats

Maushami Das (2018)

Interplay between neurokinin 1 receptor antagonist and CB2 cannabinoid receptor agonist in an animal model of neuroinflammation

2019 Shubhangi Bharati