Dr Nitesh Kumar

Assistant Professor- Selection Grade

Department of Pharmacology

CURRENT ACADEMIC ROLE & RESPONSIBILITIES

    Dr Nitesh Kumar is Assistant Professor [Selection Grade] at the Department of Pharmacology, MCOPS Manipal. Details of his research can be viewed by browsing the following links. https://scholar.google.com/citations?user=1vu3-VoAAAAJ&hl=en

    https://www.scopus.com/authid/detail.uri?authorId=25928530900

 

SUBJECTS CURRENTLY TEACHING

Subject Subject code Semester
Pharmacology 1 PHA 2.4T Second year PharmD
Pharmacology 2 PHA 3.1T Third year PharmD
Pharmacology-2 Lab PHA 3.1L Third Year PharmD
Pharmacology & Toxicology PHA 2.3 Second year DPharm
Cellular and Molecular Pharmacology PHA-MPL 104T MPharm semester-1
Pharmacology practicals PHA-MPL 105P MPharm semester-1
Pharmacology & Toxicology practical PHA2.3L Second year DPharm
Pharmacological and Toxicological Screening Methods-II PHA-MPL 202T Second semester MPharm
Pharmacology practical II PHA-MPL 205P Second semester MPharm
Research work MRW401P Third and fourth semester MPharm

ACADEMIC QUALIFICATIONS

Degree Specialisation Institute Year of passing
PhD Hepatoprotection, anticancer study Manipal College of Pharmaceutical Sciences 2013
M Pharm Pharmacology [Cancer] Manipal College of Pharmaceutical Sciences 2008
B Pharm --- Manipal College of Pharmaceutical Sciences 2006

Experience

Institution / Organisation Designation Role Tenure
Department of Pharmacology, MCOPS Manipal Assistant Professor - Selection Grade Teaching and Research 2016 till date
Department of Pharmacology, MCOPS Manipal Assistant Professor- Senior Scale Teaching and Research 2014-16
Department of Pharmacology, MCOPS Manipal Assistant Professor Teaching and Research 2013-14
Department of Pharmacology, MCOPS Manipal Lecturer Teaching and Research 2010-12
Department of Pharmacology, MCOPS Manipal Research Associate Research in a Ranbaxy sponsored project 2008-10

AREAS OF INTEREST, EXPERTISE AND RESEARCH

Area of Interest

Screening of pharmacological activity the molecules from herbal and synthetic source, Development of nano formulation (Liposomes), Toxicological study of molecules from herbal and synthetic source, Pharmacokinetic study of drugs and formulation

Area of Expertise

Toxicological studies of biomedical and pharmacutical products, In vitro and in vivo screening the molecules for anticancer, neurological, hepato-protective and hypo-lipidaemic activities , Development of Liposomes and phytosomes of herbal drugs, Pharmacokinetic study of drugs and formulation

Area of Research

In vitro and in vivo anticancer activity , Hypolipidaemic screening of herbal drugs, Development of Liposomes and phytosomes of herbal drugs, Hepatoprotective screening of herbal drugs and formulation, Pharmacokinetic study of drugs and formulation

Total number of publications: 59

A few research papers are listed below. For more details, you may kindly browse the following link- https://manipal.pure.elsevier.com/en/persons/k-nitesh

Impact of caffeic acid on aluminium chloride-induced dementia in rats

2013-01-01 Nampoothiri M Krishnadas N Rao C M Mudgal J

Journal of Pharmacy and Pharmacology, 2013.

Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumour and liquid tumour) models of cancer

2013-01-01 BS Jayashree Dhamija I Parihar V

Arabian Journal of Chemistry, 2013, Kumar, N, Dhamija, I, Raj, PV, Jayashree, BS, Parihar, V, Manjula, SN, Thomas, S, Kutty, NG, Rao C M.

An appraisal of cinnamyl sulfonamide hydroxamate derivatives (HDAC inhibitors) for anti-cancer, anti-angiogenic and anti-metastatic activities in human cancer cells

Reddy ND Shoja MH Biswas S Nayak PG Kumar N Rao CM

Chemico-biological interactions. 2016 25;253:112-24.

Preliminary evaluation of in vitro cytotoxicity and in vivo antitumor activity of Premna herbacea Roxb. in Ehrlich ascites carcinoma model and Dalton's lymphoma ascites model

2013-01-01 Parihar V Manjula SN Dhamija I

Experimental Toxicologic and Pathology, 2013.

Toxicological evaluation of Terminalia paniculata bark extract and its protective effect against CCl4-induced liver injury in rodents

2013-01-01 K Nandakumar Bansal P Shenoy RR

BMC Complementary and alternative medicine, 2013.

High carbohydrate diet with 30% sucrose solution: an optimised rodent model for simulating human insulin resistance

2013-01-01 Shenoy RR Mudgal J Rao M C

Pharmacologia, 2013.

Elucidation of structure-activity relationship of 2-quinolone derivatives and exploration of their antitumor potential through bax-induced apoptotic pathway

2012-01-01 Rao CM Raj VP Jayshree VP

Chemical Biology and Drug Design, 2012.

Synthesis and evaluation of selected 1, 3, 4-oxadiazole derivatives for in vitro cytotoxicity and in vivo anti-tumor activity

Tiwari A Kutty NG Kumar N Chaudhary A Raj PV Shenoy RR Rao CM

Cytotechnology.2016:1-15. (In Press)

Evaluation of Ceiba pentandra (L.) Gaertner bark extracts for in vitro cytotoxicity on cancer cells and in vivo antitumor activity in solid and liquid tumor models

Kumar R Kumar N Ramalingayya GV Setty MM Pai KSR

Cytotechnology.2016:1-13 (In Press)

Preliminary investigation of cytotoxic potential of 2-quinolone derivatives using in vitro and in vivo (solid tumor and liquid tumor) models of cancer

Kumar, N Dhamija, I Raj, P.V Jayashree, B.S Parihar, V Manjula, S.N Thomas, S Kutty, N.G Rao C. M

Arab. J. Chem. 2014;7(4): 409–417.

Silymarin liposomes improves oral bioavailability of silybin besides targeting hepatocytes, and immune cells

Kumar, N Rai A Reddy, N.D Raj P.V. Jain, P Deshpande, P Mathew, G Kutty, N.G Udupa, N Rao, C.M

Pharmacol. Rep. 2014; 66(5):788–798.

Insulin blocks glutamate-induced neurotoxicity in differentiated SH-SY5Y neuronal cells

Nampoothiri, M Reddy, N.D John, J. Kumar, N Kutty, Nampurath. G Rao, Chamallamudi. M

Behavioural Neurology. 2014 (2014), 1-8.

Atypical antidepressant activity of 3,4-bis(3,4-dimethoxyphenyl)furan-2,5-dione isolated from heart wood of Cedrus deodara, in rodents

Kumar, N Dhayabaran, D Nampoothiri, M Nandakumar, K. Puratchikody, A Lalani, N Dawood, K Ghosh, A

Korean. J. Physiol. Pharmacol. 2014; 18(5):365-369

Hepatoprotective role of caesalpenia bonduc: A histopathological and biochemical study

Sumalatha, S Pai, K.S Kumar, N Bhat, K.M

J Clin Diagn Res. 2014;8(11):HF05-7.

In vitro and in vivo Hepatoprotective Action of L-α-phosphatidylcholine in Alcohol-induced Toxicity Model

Raj PV Mudgal J Reddy ND Rao CM Bansal P Rai A Kumar N

International Journal of Pharmaceutical Sciences Review and Research, 2016;41(1): 171-176

In vivo evaluation of two thiazolidin-4-one derivatives in high sucrose diet fed pre-diabetic mice and their modulatory effect on AMPK, Akt and p38 MAP kinase in L6 cells

J Mudgal P Shetty Nayak PG Kumar N Kishore A Kutty NG Nandakumar K Shenoy RR Rao CM Joseph A et al

Frontiers in Pharmacology. 2016;7:381

Oral Administration of Decitabine Nanoparticles Effectively Suppresses Nmu - Induced Leukaemia in Sprague - Dawley Rats and Arrests K562 Cells in S - Phase

P Jain M Tiwari N Kumar A Chonkar JV Rao N Udupa

International Journal of Pharmaceutical and Clinical Research 8 (8), 1260 – 1268

Evaluation of Ceiba pentandra (L.) Gaertner bark extracts for in vitro cytotoxicity on cancer cells and in vivo antitumor activity in solid and liquid tumor models

Kumar R Kumar N Ramalingayya GV Setty MM Pai KSR

Cytotechnology. 2016;68(5):1909-23

Synthesis and evaluation of selected 1, 3, 4-oxadiazole derivatives for in vitro cytotoxicity and in vivo anti-tumor activity

Tiwari A Kutty NG Kumar N Chaudhary A Raj PV Shenoy RR Rao CM

Cytotechnology. 2016;68(6):2553-2565

Standardised extract of safed musli (Chlorophytum borivilianum) increases aphrodisiac potential besides being safe in male Wistar rats

Das S Singhal S Kumar N Rao CM Sumalatha S Dave J Dave R Nandakumar K

Andrologia. 2016;48(10):1236-1243

Bioequivalence study of fixed dose combination of enalapril 20mg and lercanadipine 10mg tablet in healthy human volunteers under fasting condition.

2014-01-08 Dave Sunny Kamlesh [MPharm]

The project was conducted in clinical research department of Torrent Research Centre, Bhat, Gandhi Nagar, Gujarat. The pivotal study involved assessment of bioequivalence of fixed dose combination of enalapril maleate 20 mg and lercanadipine 10mg tablet on healthy human volunteers under fasting.

Chemopreventive activity of methanolic extract of Saraca asoca bark against doxorubicin-induced toxicity

2015-03-08 Sri Pragnya Cheruku [MPharm]

We have standardized the methanolic extract of Saraca asoca bark using catechin and epicatechin as marker. The standardized extract was evaluated for chemoprotection against doxorubicin in in vitro using IMR-32 Neuroblastoma cell line and in vivo in rat [2014-2015]

Assessment of hepatoprotective effect of Megakutki, a polyherbal formulation student name

2016-06-06 Asha Elizabeth Giri

Evaluation of protective effect of Dehydrozingerone and Sesamol against diabetogenic potential of Simvastatin

2017 Girish Ghadge

Amelioration of cognitive impairment by Catechin and Dehydrozingerone in Temozolomide- induced dementia models in Wistar rats

2018 Nandini Pathak

Neuroprotective effect of Sesamol formulation against radiation- induced cognitive impairment and behavioural disorders

2018 Priyadarshini Dutta

A combination of low grade electric field application and chemotherapy: An approach of treatment in glioblastoma

2019 R J A Vibhavari