Dr Rekha R Shenoy
Associate Professor
Date of Joining: 20.01.2005
Department of Pharmacology
CURRENT ACADEMIC ROLE & RESPONSIBILITIES
- A PhD and MPharm guide currently guiding two candidates each at the doctoral and postgraduate levels
- MCOPS Website coordinator [2014 to October 2021]
- Editorial Board member, Manipal Journal of Pharmaceutical Sciences [2015 to 2019]
- Editorial team member, Manipal Academy of Higher Education Research Bulletin [2015 to June 2020]
- Editor, Ad Meliora [MCOPS e-newsletter] [2014 to Dec 2020]
- Faculty Advisor, Editorial Board, MCOPS till date
- Member of Publicity and Promotion Committee of the Administrative Council, MCOPS during 2019 to June 2021
SUBJECTS CURRENTLY TEACHING
| Subject | Semester / Year |
|---|---|
| Human Anatomy and Physiology (Theory and Lab) | First semester BPharm |
| Human Anatomy and Physiology (Theory and Lab) | Second semester BPharm |
| Clinical Research and Pharmacovigilance | 2nd semester MPharm |
| Pharmacology practicals II | 2nd semester MPharm |
| Research Methodology and Biostatistics | 3rd semester MPharm |
| Cellular and Molecular Pharmacology | First semester MPharm |
| Research work | III and IV semester MPharm |
ACADEMIC QUALIFICATIONS
| Degree | Specialisation | Institute | Year of passing |
|---|---|---|---|
| PhD | Pharmacology | Manipal Academy of Higher Education | 2010 |
| MPharm | Pharmacology | K.L.E.S’ College of Pharmacy, Belgaum | 2003 |
| BPharm | --- | College of Pharmaceutical Sciences Manipal | 2000 |
Experience
| Institution / Organisation | Designation | Role | Tenure |
|---|---|---|---|
| Department of Pharmacology, MCOPS | Associate Professor | Teaching and Research | 2014 |
| Department of Pharmacology, MCOPS | Assistant Professor Senior Scale | Teaching and Research | 2013 |
| Department of Pharmacology, MCOPS | Assistant Professor | Teaching and Research | 2010 |
| Department of Pharmacology, MCOPS | Senior Lecturer | Teaching and Research | 2008 |
| Department of Pharmacology, MCOPS | Lecturer | Teaching and Research | 2005 |
| Sree Siddaganga College of Pharmacy, Tumkur | Lecturer | Teaching | 2003 |
Elucidation of actions of naturally occurring anti-oxidants for re-structuring the skin integrity by keratinocyte migration
2015-17-03
Funded by DBT under Bio-CARe scheme [SAN No. 102/IFD/SAN/1674/2014-2015], New Delhi
Role of dehydrozingerone in wound healing: A mechanistic approach
2014-20-01
Funded by AICTE under CAYT scheme [11-24/RIFD/CAYT/POL-II/2013-14 ], New Delhi
Study of wound healing potentials of Mangiferin, Morin, Dehydrozingerone and Sesamol upon topical as well as systemic administration in albino rats
Funded by AICTE under Research promotion scheme as a Co-Investigator [completed in 2010]
AREAS OF INTEREST, EXPERTISE AND RESEARCH
Area of Interest
Wound care
Area of Expertise
Normal and diabetic wounds- preclinical
Area of Research
Oxidative Stress
Professional Affiliations & Contributions
- Distinguished Alumni Award-2016, on 13 February at ‘Awards day’ of Manipal College of Pharmaceutical Sciences, Manipal University, Manipal.
- Received the SWCR (The Society for Wound Care and Research) best paper award in the oral session, for paper titled, “Effects of Morin, Dehydrozingerone and Sesamol in normal and dexamethasone depressed dead space wounds in albino rats” in the First International Meet and Fourth Annual National Conference of SWCR (WOUND CARE CON 2010), organised by Department of Plastic Surgery, KMC, Manipal University, Manipal on 3-5 September, 2010 at Fortune Inn Valley View, Manipal.
- Life member of Indian Pharmacological Society.
- Life member of Association of Pharmaceutical Teachers of India (APTI).
- Life member of Karnataka State Pharmacy Council.
- Member of Society for Ethnopharmacology
Total number of publications: 35
Some of the important research papers are listed below. For more details, Please browse the following link- https://manipal.pure.elsevier.com/en/persons/rekha-r-shenoy
Ebola and ethics: autopsy of a failure
2015-06-05 Manthan Janodia Rekha R Shenoy Virendar Ligade Pradeep Muragundi N Udupa
British Medical Journal 2015;350:h2105 Impact factor: 17.445 (ISI Web of Science, 2015).
Iminoflavones combat 1,2- dimethyl hydrazine- induced aberrant crypt foci development in colon cancer
V. Ganga Prasad Shishir Kawade B.S. Jayashree Neetinkumar D. Reddy
Biomed Research International [2014] IF: 2.880 Volume 2014
Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-induced inflammatory bowel disorder in albino rats
Phani Krishna K Hemalatha K Geetha Mathew Pawan G
The Scientific World Journal [2014] IF: 1.730
Topical Use of Jatyadi Oil in Normal and Dexamethasone Suppressed Wound Healing in Animal Studies
Sherin Babykutty Sumisha Jose Rekha R Shenoy
2016, Research Journal of Pharmaceutical, Biological and Chemical Sciences
In vivo Evaluation of Two Thiazolidin-4-one Derivatives in High Sucrose Diet Fed Pre-diabetic Mice and Their Modulatory Effect on AMPK, Akt and p38 MAP Kinase in L6 Cells
Mudgal J Shetty P Nayak PG Kumar N Kishore A Kutty NG Nandakumar K Shenoy RR Rao CM Joseph A et al
Front Pharmacol. 2016 Oct 14;7:381
Female rats induced with mammary cancer as a relevant animal model for doxorubicin-induced chemobrain in vivo
Ramalingayya GV Nayak PG Shenoy RR Rao CM Nandakumar K
Clin Exp Pharmacol Physiol. 2016 Sep;43(9):862-3. doi: 10.1111/1440-1681.12596. No abstract available. Erratum in: Clin Exp Pharmacol Physiol. 2016 Oct;43(10):1017
Naringin and Rutin Alleviates Episodic Memory Deficits in Two Differentially Challenged Object Recognition Tasks
Ramalingayya GV Nampoothiri M Nayak PG Kishore A Shenoy RR Mallikarjuna Rao C Nandakumar K
Pharmacogn Mag. 2016 Jan;12(Suppl 1):S63-70. doi: 10.4103/0973-1296.176104.
Sambar, an Indian Dish Prevents the Development of Dimethyl Hydrazine-Induced Colon Cancer: A Preclinical Study
Prasad VG Reddy N Francis A Nayak PG Kishore A Nandakumar K Rao MC Shenoy R
Pharmacogn Mag. 2016 Jul;12(Suppl 4):S441-S445.
Epigenetic modulation of macrophage polarization- perspectives in diabetic wounds
*corresponding author Sanchari Basu Mallik B.S. Jayashree Rekha R. Shenoy*
Journal of Diabetes and Its Complications 32 (2018) 524–530
Novel flavonol analogues as potential inhibitors of JMJD3 histone demethylase—A study based on molecular modelling
*corresponding author Sanchari Basu Mallik Aravinda Pai Rekha R. Shenoy B.S. Jayashree*
Journal of Molecular Graphics and Modelling 72 (2017) 81–87
APD668, a G protein-coupled receptor 119 agonist improves fat tolerance and attenuates fatty liver in high-trans fat diet induced steatohepatitis model in C57BL/6 mice
*corresponding author Umakant Ashok Bahirat* Rekha Raghuveer Shenoy Rajan Naresh Goel Kumar V.S. Nemmani
European Journal of Pharmacology 801 (2017) 35–45
Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats
Kumar, N. , Rai, A. , Reddy, N.D. Shenoy, R.R Sharma, N. Rao, C.M. et,al
Pharmacological Reports [2019]
Neuromodulatory potential of phenylpropanoids; para-methoxycinnamic acid and ethyl-p-methoxycinnamate on aluminum-induced memory deficit in rats
Rijal, S., Changdar, N., Kinra, M., Shenoy, RR, Joseph, A., Mudgal, J.
Toxicology Mechanisms and Methods [2019]
Combination of APD668, a G protein-coupled receptor 119 agonist with linagliptin, a DPPIV inhibitor, prevents progression of steatohepatitis in a murine model of non-alcoholic steatohepatitis with diabetes
Bahirat, U.A., Talwar, R., Shenoy, R.R., Nemmani, K.V.S., Goel, R.N.
Medical Molecular Morphology [2019]
Epigenetic modulation of macrophage polarization- perspectives in diabetic wounds
Basu Mallik, S., Jayashree, B.S., Shenoy, R.R.
Journal of Diabetes and its Complications [2018]
Apoptosis induction by epidermal growth factor receptor inhibitor gefitinib in cervical cancer cell line
2012-01-01 Kolla Vennela (PG)
2012- 2013. To test the hypothesis that gefitinib induces apoptosis in cervical cancer cell line and to decode the extrinsic and intrinsic pathways of apoptosis using cell based assays and apoptotic assays.
In vitro and In vivo Evaluation of Antitumor Potential of Novel Iminoflavones
2012-01-01 Ganga Prasad [PG]
2012-2013. Detailed in vitro anticancer screening: To evaluate the apoptotic potential of Iminoflavones by varying assays such as AO/EB staining, Hoechst 33342 staining and DNA fragmentation assay, Acute toxicity studies - To assess the safety of iminoflavones in mice. In vivo anticancer study - To evaluate the antitumor potential of iminoflavones in suitable animal model. As they were showed highly potent cytotoxicity in human colon cancer cell line, 1, 2- di methyl hydrazine (DMH) induced colon cancer rat model was chosen.
Assessment of Jatyadi oil in wound healing and inflammation: A preclinical study
2013-01-01 Sherin Babykutty (PG)
2013-2014.
Evaluation of selected polyphenols for wound healing in diabetes
Karthik Gourishetti
PhD project [2015-2018]
Evaluation of synthetic myricetin analogues through epigenetic modulation of macrophage polarization in normal and diabetic wound healing
Sanchari Basu Mallik
PhD project [2015-2018]
Evaluation of antidepressant activity of soluble epoxide hydrolase inhibitor 1728 in animal models
Kalisetty Pushkala
2015-16
Assessment of soluble epoxide hydrolase inhibitors on wound models- Preclinical studies
Kamini Kumari
2015-16
Role of dehydrozingerone in wound healing: A mechanistic approach
Pallavi Toprani
2014-15
A comparative study of dietary oils for the prevention of AlCl3 induced dementia- A preclinical study
Ayush Kumar
MPharm dissertation [2016-17]
Evaluation of virgin coconut oil and sunflower oil enriched diet against colchicine induced dementia in rats
Alzheimer's disease Jeena John
MPharm Dissertation [2018-19]
Evaluation of peanut oil in colchicine induced model of dementia and its comparison with sesame oil
Sapa Naveen Kumar
MPharm Dissertation [2018-19]