Dr Rekha R Shenoy

Associate Professor

Department of Pharmacology

CURRENT ACADEMIC ROLE & RESPONSIBILITIES

    Rekha R Shenoy is an Associate Professor in the Department of Pharmacology at MCOPS.

     

    • A recognised PhD guide currently guiding three candidates
    • Website coordinator
    • Editorial team member, Manipal Academy of Higher Education Research Bulletin
    • Editor, Ad Meliora [MCOPS e-newsletter]
    • Faculty Advisor, Editorial Board, MCOPS
    • Member- Administrative Council, MCOPS

SUBJECTS CURRENTLY TEACHING

Subject Subject code Semester
Pharmacology and Toxicology (Theory and Lab) 2.3 DPharm part-II
Pharmacology-I PHA 2.4T 2nd year PharmD
Clinical Research and Pharmacovigilance PHA-MPL 204T 2nd semester MPharm
Pharmacology practicals II PHA-MPL 205P 2nd semester MPharm
Research Methodology and Biostatistics PHA-MRM301T 3rd semester MPharm
Pharmacology- 2 (Theory and Lab) PHA- 3.1T & L 3rd year PharmD
Research work MRW401P III and IV semester MPharm

ACADEMIC QUALIFICATIONS

Degree Specialisation Institute Year of passing
PhD Pharmacology Manipal Academy of Higher Education 2010
MPharm Pharmacology K.L.E.S’ College of Pharmacy, Belgaum 2003
BPharm --- College of Pharmaceutical Sciences Manipal 2000

Experience

Institution / Organisation Designation Role Tenure
Department of Pharmacology, MCOPS Associate Professor Teaching and Research 2014
Department of Pharmacology, MCOPS Assistant Professor Senior Scale Teaching and Research 2013
Department of Pharmacology, MCOPS Assistant Professor Teaching and Research 2010
Department of Pharmacology, MCOPS Senior Lecturer Teaching and Research 2008
Department of Pharmacology, MCOPS Lecturer Teaching and Research 2005
Sree Siddaganga College of Pharmacy, Tumkur Lecturer Teaching 2003

Elucidation of actions of naturally occurring anti-oxidants for re-structuring the skin integrity by keratinocyte migration

2015-17-03

Funded by DBT under Bio-CARe scheme [SAN No. 102/IFD/SAN/1674/2014-2015], New Delhi

Role of dehydrozingerone in wound healing: A mechanistic approach

2014-20-01

Funded by AICTE under CAYT scheme [11-24/RIFD/CAYT/POL-II/2013-14 ], New Delhi

Study of wound healing potentials of Mangiferin, Morin, Dehydrozingerone and Sesamol upon topical as well as systemic administration in albino rats

Funded by AICTE under Research promotion scheme as a Co-Investigator [completed in 2010]

AREAS OF INTEREST, EXPERTISE AND RESEARCH

Area of Interest

Wound care

Area of Expertise

Normal and diabetic wounds- preclinical

Area of Research

Oxidative Stress

Professional Affiliations & Contributions

  • Distinguished Alumni Award-2016, on 13 February at ‘Awards day’ of Manipal College of Pharmaceutical Sciences, Manipal University, Manipal.
  • Received the SWCR (The Society for Wound Care and Research) best paper award in the oral session, for paper titled, “Effects of Morin, Dehydrozingerone and Sesamol in normal and dexamethasone depressed dead space wounds in albino rats” in the First International Meet and Fourth Annual National Conference of SWCR (WOUND CARE CON 2010), organised by Department of Plastic Surgery, KMC, Manipal University, Manipal on 3-5 September, 2010 at Fortune Inn Valley View, Manipal.
  • Life member of Indian Pharmacological Society.
  • Life member of Association of Pharmaceutical Teachers of India (APTI).
  • Life member of Karnataka State Pharmacy Council.
  • Member of Society for Ethnopharmacology

Total number of publications: 35

Some of the important research papers are listed below. For more details, Please browse the following link- https://manipal.pure.elsevier.com/en/persons/rekha-r-shenoy

Ebola and ethics: autopsy of a failure

2015-06-05 Manthan Janodia Rekha R Shenoy Virendar Ligade Pradeep Muragundi N Udupa

British Medical Journal 2015;350:h2105 Impact factor: 17.445 (ISI Web of Science, 2015).

Iminoflavones combat 1,2- dimethyl hydrazine- induced aberrant crypt foci development in colon cancer

V. Ganga Prasad Shishir Kawade B.S. Jayashree Neetinkumar D. Reddy

Biomed Research International [2014] IF: 2.880 Volume 2014

Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-induced inflammatory bowel disorder in albino rats

Phani Krishna K Hemalatha K Geetha Mathew Pawan G

The Scientific World Journal [2014] IF: 1.730

Topical Use of Jatyadi Oil in Normal and Dexamethasone Suppressed Wound Healing in Animal Studies

Sherin Babykutty Sumisha Jose Rekha R Shenoy

2016, Research Journal of Pharmaceutical, Biological and Chemical Sciences

In vivo Evaluation of Two Thiazolidin-4-one Derivatives in High Sucrose Diet Fed Pre-diabetic Mice and Their Modulatory Effect on AMPK, Akt and p38 MAP Kinase in L6 Cells

Mudgal J Shetty P Nayak PG Kumar N Kishore A Kutty NG Nandakumar K Shenoy RR Rao CM Joseph A et al

Front Pharmacol. 2016 Oct 14;7:381

Female rats induced with mammary cancer as a relevant animal model for doxorubicin-induced chemobrain in vivo

Ramalingayya GV Nayak PG Shenoy RR Rao CM Nandakumar K

Clin Exp Pharmacol Physiol. 2016 Sep;43(9):862-3. doi: 10.1111/1440-1681.12596. No abstract available. Erratum in: Clin Exp Pharmacol Physiol. 2016 Oct;43(10):1017

Naringin and Rutin Alleviates Episodic Memory Deficits in Two Differentially Challenged Object Recognition Tasks

Ramalingayya GV Nampoothiri M Nayak PG Kishore A Shenoy RR Mallikarjuna Rao C Nandakumar K

Pharmacogn Mag. 2016 Jan;12(Suppl 1):S63-70. doi: 10.4103/0973-1296.176104.

Sambar, an Indian Dish Prevents the Development of Dimethyl Hydrazine-Induced Colon Cancer: A Preclinical Study

Prasad VG Reddy N Francis A Nayak PG Kishore A Nandakumar K Rao MC Shenoy R

Pharmacogn Mag. 2016 Jul;12(Suppl 4):S441-S445.

Epigenetic modulation of macrophage polarization- perspectives in diabetic wounds

*corresponding author Sanchari Basu Mallik B.S. Jayashree Rekha R. Shenoy*

Journal of Diabetes and Its Complications 32 (2018) 524–530

Novel flavonol analogues as potential inhibitors of JMJD3 histone demethylase—A study based on molecular modelling

*corresponding author Sanchari Basu Mallik Aravinda Pai Rekha R. Shenoy B.S. Jayashree*

Journal of Molecular Graphics and Modelling 72 (2017) 81–87

APD668, a G protein-coupled receptor 119 agonist improves fat tolerance and attenuates fatty liver in high-trans fat diet induced steatohepatitis model in C57BL/6 mice

*corresponding author Umakant Ashok Bahirat* Rekha Raghuveer Shenoy Rajan Naresh Goel Kumar V.S. Nemmani

European Journal of Pharmacology 801 (2017) 35–45

Improved in vitro and in vivo hepatoprotective effects of liposomal silymarin in alcohol-induced hepatotoxicity in Wistar rats

Kumar, N. , Rai, A. , Reddy, N.D. Shenoy, R.R Sharma, N. Rao, C.M. et,al

Pharmacological Reports [2019]

Neuromodulatory potential of phenylpropanoids; para-methoxycinnamic acid and ethyl-p-methoxycinnamate on aluminum-induced memory deficit in rats

Rijal, S., Changdar, N., Kinra, M., Shenoy, RR, Joseph, A., Mudgal, J.

Toxicology Mechanisms and Methods [2019]

Combination of APD668, a G protein-coupled receptor 119 agonist with linagliptin, a DPPIV inhibitor, prevents progression of steatohepatitis in a murine model of non-alcoholic steatohepatitis with diabetes

Bahirat, U.A., Talwar, R., Shenoy, R.R., Nemmani, K.V.S., Goel, R.N.

Medical Molecular Morphology [2019]

Epigenetic modulation of macrophage polarization- perspectives in diabetic wounds

Basu Mallik, S., Jayashree, B.S., Shenoy, R.R.

Journal of Diabetes and its Complications [2018]

Apoptosis induction by epidermal growth factor receptor inhibitor gefitinib in cervical cancer cell line

2012-01-01 Kolla Vennela (PG)

2012- 2013. To test the hypothesis that gefitinib induces apoptosis in cervical cancer cell line and to decode the extrinsic and intrinsic pathways of apoptosis using cell based assays and apoptotic assays.

In vitro and In vivo Evaluation of Antitumor Potential of Novel Iminoflavones

2012-01-01 Ganga Prasad [PG]

2012-2013. Detailed in vitro anticancer screening: To evaluate the apoptotic potential of Iminoflavones by varying assays such as AO/EB staining, Hoechst 33342 staining and DNA fragmentation assay, Acute toxicity studies - To assess the safety of iminoflavones in mice. In vivo anticancer study - To evaluate the antitumor potential of iminoflavones in suitable animal model. As they were showed highly potent cytotoxicity in human colon cancer cell line, 1, 2- di methyl hydrazine (DMH) induced colon cancer rat model was chosen.

Assessment of Jatyadi oil in wound healing and inflammation: A preclinical study

2013-01-01 Sherin Babykutty (PG)

2013-2014.

Evaluation of selected polyphenols for wound healing in diabetes

Karthik Gourishetti

PhD project [2015-2018]

Evaluation of synthetic myricetin analogues through epigenetic modulation of macrophage polarization in normal and diabetic wound healing

Sanchari Basu Mallik

PhD project [2015-2018]

Evaluation of antidepressant activity of soluble epoxide hydrolase inhibitor 1728 in animal models

Kalisetty Pushkala

2015-16

Assessment of soluble epoxide hydrolase inhibitors on wound models- Preclinical studies

Kamini Kumari

2015-16

Role of dehydrozingerone in wound healing: A mechanistic approach

Pallavi Toprani

2014-15

A comparative study of dietary oils for the prevention of AlCl3 induced dementia- A preclinical study

Ayush Kumar

MPharm dissertation [2016-17]

Evaluation of virgin coconut oil and sunflower oil enriched diet against colchicine induced dementia in rats

Alzheimer's disease Jeena John

MPharm Dissertation [2018-19]

Evaluation of peanut oil in colchicine induced model of dementia and its comparison with sesame oil

Sapa Naveen Kumar

MPharm Dissertation [2018-19]