Ms. Pooja Suresh Poojary
Lecturer
Department of Clinical Embryology
Qualification: BSc; MSc, PhD (ongoing)
CURRENT ACADEMIC ROLE & RESPONSIBILITIES
Teaching post-graduate students
Involved in IVF lab services
Effect of maternal exposure of metformin on fetal gonadal development and their reproductive potential
Metformin is a dimethylbiguanide drug prescribed for the treatment of diabetes mellitus due to its hypoglycemic activity and has an important role in reproductive medicine for the treatment of polycystic ovarian syndrome (PCOS) as it reduces androgen levels and restores ovulation. There are reports indicating that metformin can increase sex hormone binding globulin level and decrease testosterone level in maternal and fetal circulation which might alter the intrauterine environment for the growing fetus especially the male progeny. Therefore, the present study is aimed at elucidating the effect of metformin on hormonal levels, ovarian function, embryo development and reproductive potential of the progeny in diabetic and PCOS condition.
AREAS OF INTEREST, EXPERTISE AND RESEARCH
Area of Interest
Andrology, Pre-implantation embryology, Assisted Reproductive Technology (ART), Fertility Preservation
Area of Expertise
Pre-implantation embryology, Assisted Reproductive Technology (ART)
Area of Research
Male and Female infertility, Polycystic ovarian syndrome