Dr Abdul Ajees Abdul Salam

Associate Professor

Department of Atomic & Molecular Physics

CURRENT ACADEMIC ROLE & RESPONSIBILITIES

    A Abdul Ajees is Associate Professor in the Department of Atomic and Molecular Physics.

    He is:

    • Member, Board of Studies.
    • Research Coordinator, Doctoral Research Advisory Committee.
    • Member, Doctoral Research Advisory Committee.
    • Member, Project Implementation Group, FIST-2012.
    • Coordinator, Seminar Series.
    • Member, Master of Science program Syllabus Review Committee.

 

SUBJECTS CURRENTLY TEACHING

Subject Subject code Semester
Mathematical Physics and Numerical Methods. MIP 607, MSN 607, MSP 601 First Semester
Micro and Nanophotonics. MSP 608 Second Semester
Optical Materials MSP 604 Second Semester
Nanomaterial Preparation and Characterisation. MSN 602 Second Semester
Nanobiotechnology MSN 701 Third Semester
Biophotonics MIP 302, MSP 703 Third Semester

ACADEMIC QUALIFICATIONS

Degree Specialisation Institute Year of passing
Research Associate Crystallography and Biophysics Herbert Wertheim College of Medicine, Florida International University 2011
Research Associate Crystallography and Biophysics Department of Biochemistry and Molecular Biology, Wayne State University 2008
Postdoctoral Fellow Crystallography and Biophysics Centre for Biophysical Sciences and Engineering, University of Alabama 2007
PhD Crystallography and Biophysics University of Madras, Chennai, Tamil Nadu 2003
MPhil Crystallography and Biophysics University of Madras, Chennai, Tamil Nadu 1999
MSc Physics Bharathidasan University, Trichy, Tamil Nadu 1996

Experience

Institution / Organisation Designation Role Tenure
Department of Atomic and Molecular Physics Assistant Professor (Senior Scale)

AREAS OF INTEREST, EXPERTISE AND RESEARCH

Area of Interest

Structural and molecular studies on metal binding proteins

Area of Expertise

Small and macromolecule X-ray crystallography, biophysics, bioinformatics, drug identification & modelling and structural biology

Area of Research

Structural studies of arsenic binding proteins

Professional Affiliations & Contributions

  • Life member of Indian Crystallographic Association.
  • Life member of Indian Biophysical Society.
  • Executive Committee member of Post-doctoral Association, University of Alabama at Birmingham, Birmingham, Alabama, USA.
  • Student member of Indian Crystallographic Association.
  • Member of Volunteer Service Organisation.
     

The structure of an As (III) S-adenosylmethionine methyltransferase: insights into the mechanism of arsenic biotransformation

2012-01-01 Kavitha Marapakala Jie Qin Banumathi Sankaran Barry P Rosen

Biochemistry.

Life and Death with Arsenic

2011-01-01 BioEssays Timothy R McDermott

BioEssays.

Genetic mapping of the interface between the ArsD metallochaperone and the ArsA ATPase

2011-01-01 Jianbo Yang Barry P Rosen

Molecular Microbiology.

The role of alanine 163 in solute permeability of Leishmania major aquaglyceroporin LmAQP1

2011-01-01 Rita Mukhopadhyay Goutam Mandal Venkata Subba Rao Atluri Katherine Figarella

Molecular & Biochemical Parasitology.

Crystallisation and preliminary X-ray crystallographic analysis of the ArsM arsenic(III) S-adenosylmethionine methyltransferase

2010-01-01 Kavitha Marapakala Jie Qin Banumathi Sankaran Barry P Rosen

Acta Crystallographica Section F.

The 1.4 Å crystal structure of the ArsD arsenic metallochaperone provides insights into its interaction with the ArsA ATPase

2010-01-01 Jun Ye Jianbo Yang Barry P Rosen

Biochemistry.

Adventitious arsenate reductase activity of the catalytic domain of the human Cdc25B and Cdc25C Phosphatases

2010-01-01 Hiranmoy Bhattacharjee Ju Sheng Rita Mukhopadhyay Barry P Rosen

Biochemistry, Vol 49, Pg 802-809.

Role of signature lysines in the deviant walker A motif of ArsA ATPase

2010-01-10 Hsueh-Liang Fu Barry P Rosen Hiranmoy Bhattacharjee

Biochemistry, Vol 49, Pg 356-364.

Trivalent arsenicals and glucose use different translocation pathways in mammalian GLUT1

2010-01-01 Xuan Jiang, Joseph R McDermott Barry P Rosen Zijuan Liu

Metallomics, Vol 2, Pg 211-219.

Molecular simulation of ArsD, an arsenic metallochaperone with Assisted Model Building with Energy Refinement

2013-01-01 Aylin Sahin

IAESTE IndiaMIT – 2013. Both prokaryotes and eukaryotes have arsenic detoxifying systems, frequently involving extrusion from cytosol. The 120 residue ArsD is encoded by the arsRDABC operon of plasmid R773 that confers resistance to arsenite and antimonite in Escherichia coli. A molecular dynamics study was carried out to construct the missing parts of the ArsD structure. The final model will be used to examine the structure of ArsD and its interaction with the partner protein, ArsA.

Molecular simulation of ArsD, an arsenic metallochaperone with AMBER

2012-01-01 Ariana Karakutuk

IAESTE IndiaMIT – 2012. Arsenic, a toxic metalloid, causes a variety of health problems. The ArsD metallochaperone delivers trivalent metalloids, As(III) or Sb(III), to the ArsA ATPase, the catalytic subunit of the ArsAB As(III) efflux pump. In this study, we have carried out the molecular dynamics simulation experiments using AMBER program to understand the open form of ArsA as well as arsenic binding site of ArsD.

The crystallisation trials using optical forces

2012-01-01 Mahendra K

X-ray crystallography is a powerful tool for determining the three-dimensional structure of small molecules and proteins with atomic scale resolution. However, the process of producing diffraction quality crystals remains a major bottleneck in structure determination. Optically induced localised heating and consequent crystallisation method is one of the emerging technique to crystallise small molecules and proteins due to the non-contact nature as well as ability to externally control the parameters such as laser wavelength and intensity. In this work, several small molecule compounds were crystallised using an experimental setup built around an inverted Nikon microscope together with a CW Nd:YAG laser ( = 1064 nm) as an optical source.