About the Department

The Department of Gastroenterology & Hepatology started its DM Course in 2012, and from its inception is aimed at comprehensive training in clinical problem solving, logical decision making, acquiring a broad knowledge base and gaining skills in basic as well and endoscopy. The division of Gastroenterology & Hepatology at Kasturba Hospital Manipal is a highly specialized unit with advanced therapeutic endoscopy facility a state-of-the-art in-patient unit, and highly skilled gastroenterologists. The Department of Gastroenterology and Hepatology has been in existence for more than 30 years.

 It offers high end research in clinical care in pancreatic diseases and inflammatory bowel disorders.

Ours is the only tertiary care hospital in this region providing a vast exposure to our fellows in management of GI emergencies, critical care as well as in sub-specialty clinics like IBD, Liver, Pancreas or Motility. 


Adjunct Faculty

Dr. Guruprasad Padur Aithal:  Is a Professor of Hepatology and the head of the division for the Nottingham Digestive Disease center He is the Deputy Project Coordinator and work package lead of the 'Translational Safety Biomarker Pipeline (TransBioLine)' programme of the Innovation Medicines Initiative (IMI) of the European Union and the European Federation of Pharmaceutical Industries & Associations (EFPIA) (2019-24)

He is also the Hepatology lead for the National Institute for Health Research (NIHR) Health Technology Assessment programme: 'Anti-TB drug hepatotoxicity and treatment reintroduction' (2020-26).

DR. Rajvinder Singh

Dr. Rajvinder Singh is a Professor of Medicine with the University of Adelaide and the Director of Gastroenterology at the Lyell McEwin & Modbury Hospitals, South Australia.

Dr. Mohan Ramchandani

He has a passion for teaching postgraduates and interested in research, he has many publications in national and international journals. He has authored many chapters in gastroenterology textbooks. He is on the editorial board of video GIE and a peer reviewer in many GI endoscopy journals. He is active in GI endoscopy societies and presently is governing council member of the society of GI endoscopy of India and a member of the American Society of GI endoscopy. Is a consultant gastroenterologist at AIG Hospital, Hyderabad




PhD Awarded/Ongoing



Title of the grant

Granting Agency

Principal Investigator

Duration of the Project


Progression of Pancreatitis – a Prospective Follow up of Patients with Chronic,  Recurrent Acute and Acute Pancreatitis


Dr. Ganesh Pai



Identification of Novel molecular approaches to  detect idiopathic ulcerative colitis      patients at  risk of Colo-rectal malignancy


Dr. Ganesh Pai



Differences in T Lymphocytes Apoptosis in the Granulomatous Inflammation  in Intestinal Tuberculosis and crohn’s disease- implications to diagnosis and pathogenesis


Dr. Ganesh Pai



Cost of illness, quality of life and patient education in chronic non-malignant intestinal diseases





Thiopurine Therapy in Inflammatory Bowel Diseases: Optimizing Existing Strategies

Dr. Ganesh Pai C




Development of a miRNA based screening assay for hepatitis B Virus associated hepatocellular carcinoma

Dr. Shiran Shetty




Clinical Profile outcome of acute kidney injury in chronic liver disease: Role of novel biomarkers NGAL in differential diagnosis of acute kidney injury

Dr. Shiran Shetty





Services Offered

The Department of Gastroenterology & offers Consultations & Treatment for Hepatology

Hepatitis & Liver Cirrhosis
Dysphagia & Achalasia Cardia
Peptic ulcers & dyspepsia
Gastrointestinal & liver cancers
Gastrointestinal bleeding
Inflammatory bowel disorders & other intestinal diseases
Bile duct stones

Acute & chronic pancreatitis

Irritable bowel syndrome

Chronic diarrhoea, constipation

Digestive Oncology


Diagnostic Endoscopy

Gastroscopy & Colonoscopy

Endoscopic retrograde cholangiopancreatography (ERCP)

Endoscopic ultrasonography (EUS)

Capsule enteroscopy

Balloon enteroscopy


Therapeutic Endoscopy
Variceal Banding
Stricture Dilatation
Percutaneous Endoscopic Gastrostomy (PEG)
GI Stent Placement
Foreign Body Removal
Endoscopic Biliary Stone Removal
Endoscopic Biliary Stenting
Endoscopic Treatment of Pancreatic Diseases

EUS guided Therapeutic Procedures

Third space Endoscopy (ESD+POEM)

Other procedures

Oesophageal & Anorectal Manometry

Liver Biopsy



Speciality clinic

Fatty Liver

Inflammatory bowel disease





1.   Shetty A, Balaraju G, Shetty S, Pai C G, Diagnostic utility of alarm features in                    predicting malignancy with dyspeptic symptoms. Indian Journal of Gastroenterology, 2021, 40(2), 183-188


2.   Abhishek Mahajan, Athish Shetty, Prakashini Koteshwar, Balaji Musunuri, Shiran Shetty, Ganesh Bhat, Complete Regression of Hepatocelluar Carcinoma with low dose of Sorafenib. Clinical and Experimental hepatology       


3.   Khan, Z A W, Shetty S, Pai G C, Acharya K K V, Nagaraja R, Prevalence of low bone mineral density in inflammatory bowel disease and factors associated with it. Indian Journal of Gastroenterology 39(4), pp 346-353


4.   Nadella Sindhu, Prakashini Koteshwar, Shiran Shetty et al, Point Shear Wave Elastography of the Spleen in predicting the presence of Oesophageal varices in cirrhosis: Liver stiffness vs spleen stiffness journal of diagnostic medical sonography doi.org/10.1177/8756479319882006



5.   Nayak S S, Shetty M V, Pai C G, Guruprasad K P, Apoptosis in peripheral blood lymphocytes in intestinal tuberculosis and crohn’s disease: Implications to diagnostic differentiation: Indian Journal of gastroenterology 39(4), 338-345


6.   Ganesh Bhat, Athish Shetty, Aspirin use in elderly for primary prevention of cardiovascular disease: Double edged sword? : Journal of the Royal college of physicians of Edinburgh,2020, 50:403-404


7.   Ajit Sood, Vineet Ahuja, Ganehs Pai et al, Diet and inflammatory bowel disease: The Asian working group guidelines: Indian Journal of Gastroenterology doi.org/10.1007/s 12664-019-00976-1 38(3); 220-246


8.   Vignesh Shetty, Binit Lamichhane, Ganesh Pai C et al, High primary resistance to metronidazole and levofloxacin, and a moderate resistance to clarithromycin in Helicobacter pylori isolated from Karnataka patients. Shetty at al gut pathog doi..org/10.1186/s 13099-019-0305-x


9.   Shobna J Bhatia, Govind K Makharia, Indian Consensus on gastroesophageal reflux disease in adults: A position statement of the Indian Society of gastroenterology (2019) India Society of gastroenterology 35(5); 411-440


10.                Kamath N, Rajan Mallayasamy S, Sharma PSVN, Kamath A, Pai G, Effect of video assisted patient education on compliance with therapy, quality of life, psychomorbidity, and cost of illness in irritable bowel syndrome, Post graduate Medicine 131(1), 60-67




Motility at dept of gastroenterology conducts a variety of diagnostic tests to evaluate and diagnose abnormal conditions within the gastrointestinal system. Services provided include:

·         Manometry studies to evaluate motor function and coordination of muscular activity throughout the digestive system.

·         24-hour pH reflux monitoring,

·         esophageal impedance-pH monitoring for evaluation of acidic and non-acidic reflux.

·         Evaluation for constipation

·         Evaluation for difficulty in swallowing

·         Anorectal manometry and rectal biofeedback for diagnosis and treatment of anorectal dysfunction.

Advancements in the field of Gastroenterology especially related to the field of third space endoscopy lead to endoscopic cure of Achalasia with a procedure called POEM i.e, Peroral endoscopic myotomy.  POEM is akin to surgical myotomy offering a onetime cure for the disease. Procedure lasts 30-45 minutes, is incision less and offers instantaneous relief from symptoms. Resumption of oral diet can be done within one day and patient discharged the following day and no medications.

During the Endoscopic workshop held in the department of Medical Gastroenterology on 27th Feb 2021, POEM procedure was performed under the guidance of Dr. Mohan Ramchandani, Consultant Gastroenterologist from AIG Hospitals, Hyderabad. POEM was performed in this part of Karnataka for the first time. SpyGlass cholangioscopy was also performed during the workshop in several patients with complex hepatobiliary diseases including bile duct cancer for stenting, bile duct stone for crushing of stones and biliary strictures.

Our Department of Gastroenterology has state of the art latest endoscopic facilities with very affordable price. We at KMC Manipal are performing complex endoscopic diagnosis procedures like early tumour removal, pancreatic drainage, necrosectomy, and complex hepatobiliary procedures.





Contact Us


Google map: https://goo.gl/maps/C92jGMmqWh7mhkLW7

Email: gastro.kmc@manipal.edu

Phone number: 08202922192


Research & Publications

The areas of research include: Evaluation of histogenesis of various organ systems using fetal tissues. Estimation of subcutaneous fat and fibre distribution and types in the abdominal region and its clinical implications. Effect of DHA and Colin on stress induced behaviour and histological changes in the CNS. • Preventive and protective role of cissus quadrangular is extract on diabetes induced osteopenia and bone loss in osteoporosis- a cellular and molecular evaluation. Cellular and molecular mechanisms involved in curative and prophylactic role of Ceasalpenia Bonduc extracts on Liver toxicity. Use of lead as nanoparticle in traditional medicine - multi-organ approach to evaluate the functional, cellular and molecular alterations. Role of traditional medicinal preparations in wound healing - structural, biomechanical, molecular evaluations use normal and diabetic wound models.