On 14 September 2024, the Department of Pharmaceutical Biotechnology of Manipal College of Pharmaceutical Sciences organized a workshop on the "Automated Nucleic Acid Extraction - Manta" system, presented by Cambrian Bioworks. The event coordinated by Dr. Jesil Mathew A., aimed to explore advanced nucleic acid extraction techniques using automation. The principal scientist from Cambrian Bioworks demonstrated the Manta system's capabilities, focusing on its high-throughput, hands-free operation for molecular biology research and diagnostics. The live demonstration used samples including bacteriophages, bacteria, and cell lines, highlighting the system's speed and ability to process multiple samples simultaneously. Following the extraction, the DNA quality and purity were assessed using Nanodrop and Spectrostar Nano, revealing lower-than-expected results. In response, the principal scientist suggested protocol adjustments, such as modifying the lysis buffer concentration, optimizing incubation times, and refining the wash steps to improve DNA yield and purity. Despite the initial challenges, the workshop emphasized the importance of protocol optimization and provided participants with practical knowledge of automated nucleic acid extraction technologies, which hold significant potential for research and diagnostic applications.